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Chn1 chimerin 1 [ Castor canadensis (American beaver) ]

Gene ID: 109689840, updated on 14-Mar-2024

Summary

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Gene symbol
Chn1
Gene description
chimerin 1
See related
Ensembl:ENSCCNG00000030797
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017870933.1 (327157..489019, complement)

NW_017870933.1Genomic Context describing neighboring genes Neighboring gene WAS/WASL interacting protein family member 1 Neighboring gene cholinergic receptor nicotinic alpha 1 subunit Neighboring gene ATP synthase subunit g, mitochondrial pseudogene Neighboring gene activating transcription factor 2 Neighboring gene ATP synthase membrane subunit c locus 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017870933.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ephrin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in ephrin receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of small GTPase mediated signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
N-chimaerin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017870933.1 Reference C.can genome v1.0

    Range
    327157..489019 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020168892.1 → XP_020024481.1  N-chimaerin isoform X3

    UniProtKB/TrEMBL
    A0A8B7UXT2
    Conserved Domains (2) summary
    cd04372
    Location:41 → 234
    RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
    pfam00130
    Location:1 → 33
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  2. XM_020168890.1 → XP_020024479.1  N-chimaerin isoform X1

    UniProtKB/TrEMBL
    A0A8C0XQE2, A0A8C0Y2X3
    Related
    ENSCCNP00000032476.1, ENSCCNT00000040767.1
    Conserved Domains (3) summary
    cd10352
    Location:42 → 128
    SH2_a2chimerin_b2chimerin; Src homology 2 (SH2) domain found in alpha2-chimerin and beta2-chimerin proteins
    cd04372
    Location:266 → 459
    RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
    pfam00130
    Location:206 → 258
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)

  3. XM_020168891.1 → XP_020024480.1  N-chimaerin isoform X2

    UniProtKB/TrEMBL
    A0A8B7V1C0
    Conserved Domains (2) summary
    cd04372
    Location:86 → 279
    RhoGAP_chimaerin; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of chimaerins. Chimaerins are a family of phorbolester- and diacylglycerol-responsive GAPs specific for the Rho-like GTPase Rac. Chimaerins exist in two alternative splice forms ...
    pfam00130
    Location:26 → 78
    C1_1; Phorbol esters/diacylglycerol binding domain (C1 domain)
Nucleotide Protein
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