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Ncf1 neutrophil cytosolic factor 1 [ Castor canadensis (American beaver) ]

Gene ID: 109686925, updated on 14-Mar-2024

Summary

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Gene symbol
Ncf1
Gene description
neutrophil cytosolic factor 1
See related
Ensembl:ENSCCNG00000031443
Gene type
protein coding
RefSeq status
MODEL
Organism
Castor canadensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Castorimorpha; Castoridae; Castor
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current C.can genome v1.0 (GCF_001984765.1) Unplaced Scaffold NW_017869557.1 (370839..382412, complement)

NW_017869557.1Genomic Context describing neighboring genes Neighboring gene RCC1 like Neighboring gene general transcription factor II-I repeat domain-containing protein 2B-like Neighboring gene general transcription factor IIi Neighboring gene GTF2I repeat domain containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_017869557.1 Unplaced Scaffold Reference C.can genome v1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. De Novo Genome and Transcriptome Assembly of the Canadian Beaver (Castor canadensis). Lok S, et al. G3 (Bethesda), 2017 Feb 9. PMID 28087693, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables superoxide-generating NADPH oxidase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in respiratory burst IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neutrophil cytosol factor 1
Names
neutrophil cytosol factor 1-like protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Castor canadensis Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference C.can genome v1.0

Genomic

  1. NW_017869557.1 Reference C.can genome v1.0

    Range
    370839..382412 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_020164492.1 → XP_020020081.1  neutrophil cytosol factor 1

    UniProtKB/TrEMBL
    A0A250YH43, A0A8C0XYI4
    Related
    ENSCCNP00000033200.1, ENSCCNT00000041651.1
    Conserved Domains (4) summary
    cd06887
    Location:6 → 123
    PX_p47phox; The phosphoinositide binding Phox Homology domain of the p47phox subunit of NADPH oxidase
    cd12021
    Location:160 → 212
    SH3_p47phox_1; First or N-terminal Src homology 3 domain of the p47phox subunit of NADPH oxidase, also called Neutrophil Cytosolic Factor 1
    cd12022
    Location:230 → 282
    SH3_p47phox_2; Second or C-terminal Src homology 3 domain of the p47phox subunit of NADPH oxidase, also called Neutrophil Cytosolic Factor 1
    pfam16621
    Location:282 → 331
    NECFESHC; SH3 terminal domain of 2nd SH3 on Neutrophil cytosol factor 1
Nucleotide Protein
Heading Accession and Version

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