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SCN1A sodium voltage-gated channel alpha subunit 1 [ Bos indicus (zebu cattle) ]

Gene ID: 109566928, updated on 14-Mar-2024

Summary

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Gene symbol
SCN1A
Gene description
sodium voltage-gated channel alpha subunit 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos indicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
26
Annotation release Status Assembly Chr Location
100 current Bos_indicus_1.0 (GCF_000247795.1) 2 NC_032651.1 (31252817..31348670)

Chromosome 2 - NC_032651.1Genomic Context describing neighboring genes Neighboring gene sodium voltage-gated channel alpha subunit 7 Neighboring gene sodium voltage-gated channel alpha subunit 9 Neighboring gene regulator of microtubule dynamics 1 Neighboring gene tetratricopeptide repeat domain 21B Neighboring gene polypeptide N-acetylgalactosaminyltransferase 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032651.1 Chromosome 2 Reference Bos_indicus_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated sodium channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in membrane depolarization during action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuronal action potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in sodium ion transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of voltage-gated sodium channel complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sodium channel protein type 1 subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos indicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_indicus_1.0 Primary Assembly

Genomic

  1. NC_032651.1 Reference Bos_indicus_1.0 Primary Assembly

    Range
    31252817..31348670
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019971672.1 → XP_019827231.1  sodium channel protein type 1 subunit alpha isoform X2

    UniProtKB/TrEMBL
    A0A6P5CM99
    Conserved Domains (5) summary
    cd13433
    Location:1484 → 1536
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1217 → 1492
    Ion_trans; Ion transport protein
    pfam06512
    Location:1006 → 1213
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:510 → 705
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1800 → 1863
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated

  2. XM_019971663.1 → XP_019827222.1  sodium channel protein type 1 subunit alpha isoform X1

    UniProtKB/TrEMBL
    A0A6P5CQR5
    Conserved Domains (5) summary
    cd13433
    Location:1473 → 1525
    Na_channel_gate; Inactivation gate of the voltage-gated sodium channel alpha subunits
    pfam00520
    Location:1206 → 1481
    Ion_trans; Ion transport protein
    pfam06512
    Location:995 → 1202
    Na_trans_assoc; Sodium ion transport-associated
    pfam11933
    Location:510 → 694
    Na_trans_cytopl; Cytoplasmic domain of voltage-gated Na+ ion channel
    pfam16905
    Location:1789 → 1852
    GPHH; Voltage-dependent L-type calcium channel, IQ-associated
Nucleotide Protein
Heading Accession and Version

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