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FXR1 FMR1 autosomal homolog 1 [ Bos indicus (zebu cattle) ]

Gene ID: 109557731, updated on 14-Mar-2024

Summary

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Gene symbol
FXR1
Gene description
FMR1 autosomal homolog 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Bos indicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bos
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
17
Annotation release Status Assembly Chr Location
100 current Bos_indicus_1.0 (GCF_000247795.1) 1 NC_032650.1 (88128802..88202796, complement)

Chromosome 1 - NC_032650.1Genomic Context describing neighboring genes Neighboring gene elongation factor 1-alpha, oocyte form-like Neighboring gene DnaJ heat shock protein family (Hsp40) member C19 Neighboring gene transfer RNA cysteine (anticodon ACA) Neighboring gene coiled-coil domain 39 molecular ruler complex subunit

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_032650.1 Chromosome 1 Reference Bos_indicus_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mRNA 3'-UTR binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables translation regulator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in anterograde axonal transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in central nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of translation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of alternative mRNA splicing, via spliceosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendrite morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of dendritic spine development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of filopodium assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of mRNA stability IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of modification of synaptic structure IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of translation at postsynapse, modulating synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic filopodium IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine neck IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in growth cone IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal cell body IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuronal ribonucleoprotein granule IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in presynapse IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fragile X mental retardation syndrome-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bos indicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bos_indicus_1.0 Primary Assembly

Genomic

  1. NC_032650.1 Reference Bos_indicus_1.0 Primary Assembly

    Range
    88128802..88202796 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019959213.1 → XP_019814772.1  fragile X mental retardation syndrome-related protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A6P5BKW0
    Conserved Domains (8) summary
    pfam12235
    Location:354 → 465
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:491 → 564
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:583 → 649
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    cd20472
    Location:3 → 57
    Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd20475
    Location:61 → 126
    Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22504
    Location:123 → 199
    KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22507
    Location:218 → 280
    KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22510
    Location:281 → 358
    KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

  2. XM_019959211.1 → XP_019814770.1  fragile X mental retardation syndrome-related protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A6P5BRA0
    Conserved Domains (8) summary
    pfam12235
    Location:354 → 465
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:491 → 564
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:610 → 676
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    cd20472
    Location:3 → 57
    Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd20475
    Location:61 → 126
    Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22504
    Location:123 → 199
    KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22507
    Location:218 → 280
    KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22510
    Location:281 → 358
    KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

  3. XM_019959232.1 → XP_019814791.1  fragile X mental retardation syndrome-related protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A6P5BCS2
    Conserved Domains (8) summary
    pfam12235
    Location:354 → 436
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:462 → 535
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:554 → 620
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    cd20472
    Location:3 → 57
    Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd20475
    Location:61 → 126
    Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22504
    Location:123 → 199
    KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22507
    Location:218 → 280
    KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22510
    Location:281 → 358
    KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

  4. XM_019959250.1 → XP_019814809.1  fragile X mental retardation syndrome-related protein 1 isoform X6

    UniProtKB/TrEMBL
    A0A6P5BR73
    Conserved Domains (7) summary
    pfam12235
    Location:354 → 465
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:491 → 564
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    cd20472
    Location:3 → 57
    Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd20475
    Location:61 → 126
    Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22504
    Location:123 → 199
    KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22507
    Location:218 → 280
    KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22510
    Location:281 → 358
    KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

  5. XM_019959241.1 → XP_019814800.1  fragile X mental retardation syndrome-related protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A6P5BRB1
    Conserved Domains (7) summary
    cd20472
    Location:3 → 57
    Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd20475
    Location:61 → 126
    Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22504
    Location:123 → 199
    KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22507
    Location:218 → 280
    KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22510
    Location:281 → 358
    KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    pfam12235
    Location:354 → 467
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:491 → 564
    FXR_C1; Fragile X-related 1 protein C-terminal region 2

  6. XM_019959257.1 → XP_019814816.1  fragile X mental retardation syndrome-related protein 1 isoform X7

    UniProtKB/TrEMBL
    A0A6P5BCU4
    Conserved Domains (7) summary
    pfam12235
    Location:354 → 436
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:462 → 535
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    cd20472
    Location:3 → 57
    Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd20475
    Location:61 → 126
    Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22504
    Location:123 → 199
    KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22507
    Location:218 → 280
    KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22510
    Location:281 → 358
    KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins

  7. XM_019959222.1 → XP_019814781.1  fragile X mental retardation syndrome-related protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A6P5BCR0
    Conserved Domains (8) summary
    pfam12235
    Location:354 → 436
    FXMRP1_C_core; Fragile X-related 1 protein core C terminal
    pfam16096
    Location:462 → 535
    FXR_C1; Fragile X-related 1 protein C-terminal region 2
    pfam16097
    Location:581 → 647
    FXR_C3; Fragile X-related 1 protein C-terminal region 3
    cd20472
    Location:3 → 57
    Tudor_Agenet_FXR1_rpt1; first Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd20475
    Location:61 → 126
    Tudor_Agenet_FXR1_rpt2; second Tudor-like Agenet domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22504
    Location:123 → 199
    KH_I_FXR1_rpt1; first type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22507
    Location:218 → 280
    KH_I_FXR1_rpt2; second type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
    cd22510
    Location:281 → 358
    KH_I_FXR1_rpt3; third type I K homology (KH) RNA-binding domain found in fragile X mental retardation syndrome-related protein 1 (FXR1) and similar proteins
Nucleotide Protein
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