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CCL5 C-C motif chemokine ligand 5 [ Panthera pardus (leopard) ]

Gene ID: 109251958, updated on 14-Mar-2024

Summary

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Gene symbol
CCL5
Gene description
C-C motif chemokine ligand 5
See related
Ensembl:ENSPPRG00000022842
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera pardus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
RS_2023_02 current ASM2436296v1 (GCF_024362965.1) Unplaced Scaffold NW_026526876.1 (50789459..50796137)
100 previous assembly PanPar1.0 (GCF_001857705.1) Unplaced Scaffold NW_017619941.1 (6247853..6255971, complement)

NW_026526876.1Genomic Context describing neighboring genes Neighboring gene C-C motif chemokine 14 Neighboring gene uncharacterized LOC109251962 Neighboring gene C-C motif chemokine ligand 16 Neighboring gene HEAT repeat containing 9 Neighboring gene TATA-box binding protein associated factor 15 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables CCR chemokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chemokine activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in G protein-coupled receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to interleukin-1 IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to tumor necrosis factor IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to type II interferon IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in chemokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in lymphocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neutrophil chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of T cell chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
C-C motif chemokine 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_024362965.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM2436296v1 Primary Assembly

Genomic

  1. NW_026526876.1 Reference ASM2436296v1 Primary Assembly

    Range
    50789459..50796137
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_019423978.2 → XP_019279523.1  C-C motif chemokine 5

    UniProtKB/TrEMBL
    A0A9V1EDR5
    Related
    ENSPPRP00000003347.1
    Conserved Domains (1) summary
    cd00272
    Location:33 → 89
    Chemokine_CC; 1 of 4 subgroup designations based on the arrangement of the two N-terminal cysteine residues; includes a number of secreted growth factors and interferons involved in mitogenic, chemotactic, and inflammatory activity; some members (e.g. 2HCC) contain an ...
Nucleotide Protein
Heading Accession and Version

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