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ACTN4 actinin alpha 4 [ Rhinopithecus bieti (black snub-nosed monkey) ]

Gene ID: 108539029, updated on 1-Aug-2024

Summary

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Gene symbol
ACTN4
Gene description
actinin alpha 4
See related
Ensembl:ENSRBIG00000040525
Gene type
protein coding
RefSeq status
MODEL
Organism
Rhinopithecus bieti
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Colobinae; Rhinopithecus
Orthologs
human mouse all
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Genomic context

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See ACTN4 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current ASM169854v1 (GCF_001698545.1) Unplaced Scaffold NW_016808836.1 (461554..546943)

NW_016808836.1Genomic Context describing neighboring genes Neighboring gene mitogen-activated protein kinase kinase kinase kinase 1 Neighboring gene eukaryotic translation initiation factor 3 subunit K Neighboring gene calpain 12 Neighboring gene galectin-7 Neighboring gene galectin-7-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_016808836.1 Unplaced Scaffold Reference ASM169854v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in muscle cell development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Z disc IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
alpha-actinin-4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Rhinopithecus bieti Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM169854v1 Primary Assembly

Genomic

  1. NW_016808836.1 Reference ASM169854v1 Primary Assembly

    Range
    461554..546943
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017887412.1 → XP_017742901.1  alpha-actinin-4 isoform X1

    UniProtKB/TrEMBL
    A0A2K6ME12, A0A2K6ME80, A0AAJ7MU50
    Related
    ENSRBIP00000034001.1, ENSRBIT00000057985.1
    Conserved Domains (5) summary
    PTZ00184
    Location:759 → 868
    PTZ00184; calmodulin; Provisional
    cd00176
    Location:414 → 640
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam08726
    Location:841 → 907
    EFhand_Ca_insen; Ca2+ insensitive EF hand
    cd21214
    Location:47 → 151
    CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
    cd21216
    Location:155 → 269
    CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family

  2. XM_017887413.1 → XP_017742902.1  alpha-actinin-4 isoform X2

    UniProtKB/TrEMBL
    A0A2K6MDZ3, A0A2K6ME80, A0AAJ7MU39
    Related
    ENSRBIP00000034008.1, ENSRBIT00000057992.1
    Conserved Domains (5) summary
    PTZ00184
    Location:759 → 868
    PTZ00184; calmodulin; Provisional
    cd00176
    Location:414 → 640
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam08726
    Location:841 → 907
    EFhand_Ca_insen; Ca2+ insensitive EF hand
    cd21214
    Location:47 → 151
    CH_ACTN_rpt1; first calponin homology (CH) domain found in the alpha-actinin family
    cd21216
    Location:155 → 269
    CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family

  3. XM_017887414.1 → XP_017742903.1  alpha-actinin-4 isoform X3

    UniProtKB/TrEMBL
    A0A2K6ME20, A0AAJ7MU37
    Related
    ENSRBIP00000034044.1, ENSRBIT00000058028.1
    Conserved Domains (5) summary
    PTZ00184
    Location:675 → 784
    PTZ00184; calmodulin; Provisional
    cd00176
    Location:330 → 556
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    pfam08726
    Location:757 → 823
    EFhand_Ca_insen; Ca2+ insensitive EF hand
    cd21216
    Location:71 → 185
    CH_ACTN_rpt2; second calponin homology (CH) domain found in the alpha-actinin family
    cl00030
    Location:1 → 67
    CH_SF; calponin homology (CH) domain superfamily

  4. XM_017887415.1 → XP_017742904.1  alpha-actinin-4 isoform X4

    UniProtKB/TrEMBL
    A0AAJ7MUP8
    Related
    ENSRBIP00000034041.1, ENSRBIT00000058025.1
Nucleotide Protein
Heading Accession and Version

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