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pde8a phosphodiesterase 8A [ Pygocentrus nattereri (red-bellied piranha) ]

Gene ID: 108413144, updated on 12-Sep-2024

Summary

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Gene symbol
pde8a
Gene description
phosphodiesterase 8A
See related
Ensembl:ENSPNAG00000009666
Gene type
protein coding
RefSeq status
MODEL
Organism
Pygocentrus nattereri
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Ostariophysi; Characiformes; Characoidei; Pygocentrus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 7
Exon count:
22
Annotation release Status Assembly Chr Location
101 current fPygNat1.pri (GCF_015220715.1) 7 NC_051217.1 (47257380..47340726)
100 previous assembly Pygocentrus_nattereri-1.0.2 (GCF_001682695.1) Unplaced Scaffold NW_016244866.1 (3176..23757)

Chromosome 7 - NC_051217.1Genomic Context describing neighboring genes Neighboring gene very long-chain acyl-CoA synthetase-like Neighboring gene glycine amidinotransferase (L-arginine:glycine amidinotransferase) Neighboring gene KH homology domain-containing protein 4-like Neighboring gene fibronectin type III and SPRY domain-containing protein 2 Neighboring gene WASP homolog associated with actin, golgi membranes and microtubules

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3',5'-cyclic-AMP phosphodiesterase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to epidermal growth factor stimulus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pygocentrus nattereri Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference fPygNat1.pri

Genomic

  1. NC_051217.1 Reference fPygNat1.pri

    Range
    47257380..47340726
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037539929.1 → XP_037395826.1  high affinity cAMP-specific and IBMX-insensitive 3',5'-cyclic phosphodiesterase 8A

    UniProtKB/TrEMBL
    A0A3B4BU21
    Related
    ENSPNAP00000003147.2, ENSPNAT00000009213.2
    Conserved Domains (4) summary
    pfam00233
    Location:533 → 784
    PDEase_I; 3'5'-cyclic nucleotide phosphodiesterase
    pfam08629
    Location:1 → 42
    PDE8; PDE8 phosphodiesterase
    cl19078
    Location:63 → 163
    REC; phosphoacceptor receiver (REC) domain of response regulators (RRs) and pseudo response regulators (PRRs)
    cl21578
    Location:200 → 320
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
Nucleotide Protein
Heading Accession and Version

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