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MCC MCC regulator of WNT signaling pathway [ Manis javanica (Malayan pangolin) ]

Gene ID: 108408631, updated on 14-Mar-2024

Summary

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Gene symbol
MCC
Gene description
MCC regulator of WNT signaling pathway
Gene type
protein coding
RefSeq status
MODEL
Organism
Manis javanica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Pholidota; Manidae; Manis
Orthologs
human mouse all
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Genomic context

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See MCC in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
101 current YNU_ManJav_2.0 (GCF_014570535.1) Unplaced Scaffold NW_023436164.1 (1588211..1972215, complement)
100 previous assembly ManJav1.0 (GCF_001685135.1) Unplaced Scaffold NW_016528180.1 (178012..281734, complement)

NW_023436164.1Genomic Context describing neighboring genes Neighboring gene translation initiation factor IF-2-like Neighboring gene U6 spliceosomal RNA Neighboring gene decapping mRNA 2 Neighboring gene uncharacterized LOC108404488 Neighboring gene protein FAM193B-like Neighboring gene family with sequence similarity 193 member B Neighboring gene DEAD-box helicase 41

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of canonical Wnt signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
colorectal mutant cancer protein
Names
MCC, WNT signaling pathway regulator
mutated in colorectal cancers

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Manis javanica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference YNU_ManJav_2.0 Primary Assembly

Genomic

  1. NW_023436164.1 Reference YNU_ManJav_2.0 Primary Assembly

    Range
    1588211..1972215 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_036995125.1 → XP_036851020.1  colorectal mutant cancer protein isoform X1

    Conserved Domains (3) summary
    COG1196
    Location:197 → 1014
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10506
    Location:587 → 651
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
    pfam13499
    Location:30 → 86
    EF-hand_7; EF-hand domain pair

  2. XM_036995126.1 → XP_036851021.1  colorectal mutant cancer protein isoform X2

    Conserved Domains (2) summary
    COG1196
    Location:572 → 843
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10506
    Location:416 → 480
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome

  3. XM_036995127.1 → XP_036851022.1  colorectal mutant cancer protein isoform X2

    Conserved Domains (2) summary
    COG1196
    Location:572 → 843
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10506
    Location:416 → 480
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome

  4. XM_036995129.1 → XP_036851024.1  colorectal mutant cancer protein isoform X4

    Conserved Domains (2) summary
    COG1196
    Location:557 → 828
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10506
    Location:401 → 465
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome

  5. XM_036995128.1 → XP_036851023.1  colorectal mutant cancer protein isoform X3

    Conserved Domains (2) summary
    COG1196
    Location:11 → 256
    Smc; Chromosome segregation ATPase [Cell cycle control, cell division, chromosome partitioning]
    pfam10506
    Location:412 → 476
    MCC-bdg_PDZ; PDZ domain of MCC-2 bdg protein for Usher syndrome
Nucleotide Protein
Heading Accession and Version

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