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CLCNKA chloride voltage-gated channel Ka [ Coturnix japonica (Japanese quail) ]

Gene ID: 107323319, updated on 14-Mar-2024

Summary

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Gene symbol
CLCNKA
Gene description
chloride voltage-gated channel Ka
Gene type
protein coding
RefSeq status
MODEL
Organism
Coturnix japonica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Perdicinae; Coturnix
Orthologs
human all
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Genomic context

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Location:
chromosome: 21
Exon count:
19
Annotation release Status Assembly Chr Location
101 current Coturnix japonica 2.1 (GCF_001577835.2) 21 NC_029536.1 (3727492..3732727)

Chromosome 21 - NC_029536.1Genomic Context describing neighboring genes Neighboring gene zinc finger and BTB domain containing 17 Neighboring gene heat shock protein family B (small) member 7 Neighboring gene EPH receptor A2 Neighboring gene ciliogenesis and planar polarity effector complex subunit 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_029536.1 Chromosome 21 Reference Coturnix japonica 2.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables voltage-gated chloride channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chloride transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in transmembrane transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
chloride channel protein ClC-Ka

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Coturnix japonica Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Coturnix japonica 2.1 Primary Assembly

Genomic

  1. NC_029536.1 Reference Coturnix japonica 2.1 Primary Assembly

    Range
    3727492..3732727
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015882278.2 → XP_015737764.1  chloride channel protein ClC-Ka isoform X1

    UniProtKB/TrEMBL
    A0A8C2U5K9
    Conserved Domains (3) summary
    cd03683
    Location:47 → 532
    ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
    cd04591
    Location:563 → 678
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
    pfam00654
    Location:103 → 495
    Voltage_CLC; Voltage gated chloride channel

  2. XM_015882280.2 → XP_015737766.1  chloride channel protein ClC-Ka isoform X2

    UniProtKB/TrEMBL
    A0A8C2U5K9
    Conserved Domains (3) summary
    cd03683
    Location:47 → 495
    ClC_1_like; ClC-1-like chloride channel proteins. This CD includes isoforms ClC-0, ClC-1, ClC-2 and ClC_K. ClC-1 is expressed in skeletal muscle and its mutation leads to both recessively and dominantly-inherited forms of muscle stiffness or myotonia. ClC-K is ...
    cd04591
    Location:526 → 641
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
    pfam00654
    Location:103 → 458
    Voltage_CLC; Voltage gated chloride channel

  3. XM_015882281.2 → XP_015737767.1  chloride channel protein ClC-Ka isoform X3

    UniProtKB/TrEMBL
    A0A8C2U5K9
    Conserved Domains (3) summary
    cd04591
    Location:521 → 636
    CBS_pair_EriC_assoc_euk_bac; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains in the EriC CIC-type chloride channels in eukaryotes and bacteria. These ion channels are proteins with a seemingly simple task of allowing the passive flow of ...
    pfam00654
    Location:103 → 453
    Voltage_CLC; Voltage gated chloride channel
    cl02915
    Location:47 → 490
    Voltage_gated_ClC; CLC voltage-gated chloride channel. The ClC chloride channels catalyse the selective flow of Cl- ions across cell membranes, thereby regulating electrical excitation in skeletal muscle and the flow of salt and water across epithelial barriers. This ...
Nucleotide Protein
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