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MITF melanocyte inducing transcription factor [ Protobothrops mucrosquamatus ]

Gene ID: 107297236, updated on 14-Mar-2024

Summary

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Gene symbol
MITF
Gene description
melanocyte inducing transcription factor
Gene type
protein coding
RefSeq status
MODEL
Organism
Protobothrops mucrosquamatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Colubroidea; Viperidae; Crotalinae; Protobothrops
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
101 current P.Mucros_1.0 (GCF_001527695.2) Unplaced Scaffold NW_015389196.1 (13265..66151, complement)

NW_015389196.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015389196 Unplaced Scaffold Reference P.Mucros_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in melanocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
microphthalmia-associated transcription factor
Names
melanogenesis associated transcription factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Protobothrops mucrosquamatus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.Mucros_1.0 Primary Assembly

Genomic

  1. NW_015389196.1 Reference P.Mucros_1.0 Primary Assembly

    Range
    13265..66151 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015826598.1 → XP_015682084.1  microphthalmia-associated transcription factor isoform X5

    Conserved Domains (4) summary
    cd00083
    Location:252 → 312
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:340 → 467
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:4 → 142
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:308 → 343
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  2. XM_029286258.1 → XP_029142091.1  microphthalmia-associated transcription factor isoform X4

    Conserved Domains (4) summary
    cd00083
    Location:258 → 318
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:346 → 473
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:4 → 142
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:314 → 349
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  3. XM_015826596.1 → XP_015682082.1  microphthalmia-associated transcription factor isoform X3

    Conserved Domains (3) summary
    cd00083
    Location:141 → 201
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:229 → 356
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:11 → 31
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  4. XM_015826595.1 → XP_015682081.1  microphthalmia-associated transcription factor isoform X2

    Conserved Domains (4) summary
    cd00083
    Location:197 → 257
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:285 → 412
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:11 → 87
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:253 → 288
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain

  5. XM_015826594.1 → XP_015682080.1  microphthalmia-associated transcription factor isoform X1

    Conserved Domains (4) summary
    cd00083
    Location:203 → 263
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:291 → 418
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:11 → 87
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
    cl21462
    Location:259 → 294
    bZIP; Basic leucine zipper (bZIP) domain of bZIP transcription factors: a DNA-binding and dimerization domain
Nucleotide Protein
Heading Accession and Version

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