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DLG3 discs large MAGUK scaffold protein 3 [ Parus major (Great Tit) ]

Gene ID: 107203904, updated on 3-Aug-2024

Summary

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Gene symbol
DLG3
Gene description
discs large MAGUK scaffold protein 3
See related
Ensembl:ENSPMJG00000011462
Gene type
protein coding
RefSeq status
MODEL
Organism
Parus major
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Paridae; Parus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4A
Exon count:
30
Annotation release Status Assembly Chr Location
102 current Parus_major1.1 (GCF_001522545.3) 4A NC_031772.1 (15555595..15634011)
100 previous assembly Parus_major1.0.3 (GCF_001522545.1) 4A NC_029272.1 (15555595..15634011)

Chromosome 4A - NC_031772.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC117244341 Neighboring gene 5-hydroxytryptamine receptor 2C Neighboring gene uncharacterized LOC107203906 Neighboring gene glycerophosphodiester phosphodiesterase domain containing 2 Neighboring gene nuclear cap-binding protein subunit 2 Neighboring gene testis expressed 11

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables kinase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuromuscular junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic density membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
disks large homolog 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Parus major Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Parus_major1.1 Primary Assembly

Genomic

  1. NC_031772.1 Reference Parus_major1.1 Primary Assembly

    Range
    15555595..15634011
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015626495.1 → XP_015481981.1  disks large homolog 3 isoform X1

    Related
    ENSPMJP00000015121.1, ENSPMJT00000019854.1
    Conserved Domains (7) summary
    cd12029
    Location:552 → 618
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:719 → 886
    GuKc; Guanylate kinase homologues
    cd00992
    Location:434 → 512
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:708 → 886
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:3 → 59
    L27_1; L27_1
    pfam10600
    Location:361 → 435
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:118 → 180
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  2. XM_015626496.1 → XP_015481982.1  disks large homolog 3 isoform X1

    Conserved Domains (7) summary
    cd12029
    Location:552 → 618
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:719 → 886
    GuKc; Guanylate kinase homologues
    cd00992
    Location:434 → 512
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:708 → 886
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:3 → 59
    L27_1; L27_1
    pfam10600
    Location:361 → 435
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:118 → 180
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  3. XM_019006543.1 → XP_018862088.1  disks large homolog 3 isoform X2

    Related
    ENSPMJP00000015122.1, ENSPMJT00000019855.1

  4. XM_015626498.1 → XP_015481984.1  disks large homolog 3 isoform X4

    Conserved Domains (7) summary
    cd12029
    Location:552 → 618
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:701 → 868
    GuKc; Guanylate kinase homologues
    cd00992
    Location:434 → 512
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:690 → 868
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:3 → 59
    L27_1; L27_1
    pfam10600
    Location:361 → 435
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:118 → 180
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  5. XM_015626500.1 → XP_015481986.1  disks large homolog 3 isoform X5

    Conserved Domains (7) summary
    cd12029
    Location:552 → 618
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:687 → 854
    GuKc; Guanylate kinase homologues
    cd00992
    Location:434 → 512
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:676 → 854
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:3 → 59
    L27_1; L27_1
    pfam10600
    Location:361 → 435
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:118 → 180
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  6. XM_015626499.1 → XP_015481985.1  disks large homolog 3 isoform X3

    Related
    ENSPMJP00000015123.1, ENSPMJT00000019856.1
    Conserved Domains (6) summary
    cd12029
    Location:534 → 600
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:701 → 868
    GuKc; Guanylate kinase homologues
    cd00992
    Location:416 → 494
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:690 → 868
    Guanylate_kin; Guanylate kinase
    pfam09058
    Location:3 → 59
    L27_1; L27_1
    pfam10600
    Location:343 → 417
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  7. XM_015626502.3 → XP_015481988.1  disks large homolog 3 isoform X7

    Related
    ENSPMJP00000015124.1, ENSPMJT00000019857.1
    Conserved Domains (6) summary
    cd12029
    Location:508 → 574
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:675 → 842
    GuKc; Guanylate kinase homologues
    cd00992
    Location:390 → 468
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:664 → 842
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:317 → 391
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:74 → 136
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  8. XM_015626505.3 → XP_015481991.1  disks large homolog 3 isoform X10

    Conserved Domains (6) summary
    cd12029
    Location:510 → 576
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:645 → 812
    GuKc; Guanylate kinase homologues
    cd00992
    Location:392 → 470
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:634 → 812
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:319 → 393
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:98 → 138
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  9. XM_015626504.3 → XP_015481990.1  disks large homolog 3 isoform X9

    Related
    ENSPMJP00000015126.1, ENSPMJT00000019859.1
    Conserved Domains (6) summary
    cd12029
    Location:510 → 576
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:659 → 826
    GuKc; Guanylate kinase homologues
    cd00992
    Location:392 → 470
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:648 → 826
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:319 → 393
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:98 → 138
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  10. XM_015626506.3 → XP_015481992.1  disks large homolog 3 isoform X11

    Related
    ENSPMJP00000015127.1, ENSPMJT00000019860.1
    Conserved Domains (5) summary
    cd12029
    Location:492 → 558
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:627 → 794
    GuKc; Guanylate kinase homologues
    cd00992
    Location:374 → 452
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:616 → 794
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:301 → 375
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  11. XM_015626501.3 → XP_015481987.1  disks large homolog 3 isoform X6

    Conserved Domains (6) summary
    cd12029
    Location:510 → 576
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:677 → 844
    GuKc; Guanylate kinase homologues
    cd00992
    Location:392 → 470
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:666 → 844
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:319 → 393
    PDZ_assoc; PDZ-associated domain of NMDA receptors
    pfam10608
    Location:98 → 138
    MAGUK_N_PEST; Polyubiquitination (PEST) N-terminal domain of MAGUK

  12. XM_015626503.3 → XP_015481989.1  disks large homolog 3 isoform X8

    Related
    ENSPMJP00000015125.1, ENSPMJT00000019858.1
    Conserved Domains (5) summary
    cd12029
    Location:492 → 558
    SH3_DLG3; Src Homology 3 domain of Disks Large homolog 3
    smart00072
    Location:659 → 826
    GuKc; Guanylate kinase homologues
    cd00992
    Location:374 → 452
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00625
    Location:648 → 826
    Guanylate_kin; Guanylate kinase
    pfam10600
    Location:301 → 375
    PDZ_assoc; PDZ-associated domain of NMDA receptors

  13. XM_015626507.2 → XP_015481993.1  disks large homolog 3 isoform X12

    Conserved Domains (2) summary
    pfam00625
    Location:175 → 353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:19 → 85
    SH3; Src Homology 3 domain superfamily

  14. XM_015626509.3 → XP_015481995.1  disks large homolog 3 isoform X12

    Conserved Domains (2) summary
    pfam00625
    Location:175 → 353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:19 → 85
    SH3; Src Homology 3 domain superfamily

  15. XM_015626508.3 → XP_015481994.1  disks large homolog 3 isoform X12

    Conserved Domains (2) summary
    pfam00625
    Location:175 → 353
    Guanylate_kin; Guanylate kinase
    cl17036
    Location:19 → 85
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
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