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HMGCS1 3-hydroxy-3-methylglutaryl-CoA synthase 1 [ Parus major (Great Tit) ]

Gene ID: 107198226, updated on 3-Aug-2024

Summary

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Gene symbol
HMGCS1
Gene description
3-hydroxy-3-methylglutaryl-CoA synthase 1
See related
Ensembl:ENSPMJG00000015863
Gene type
protein coding
RefSeq status
MODEL
Organism
Parus major
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Telluraves; Australaves; Passeriformes; Paridae; Parus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
11
Annotation release Status Assembly Chr Location
102 current Parus_major1.1 (GCF_001522545.3) Z NC_031799.1 (13510386..13521562, complement)
100 previous assembly Parus_major1.0.3 (GCF_001522545.1) Z NC_029299.1 (13510382..13521583, complement)

Chromosome Z - NC_031799.1Genomic Context describing neighboring genes Neighboring gene selenoprotein P Neighboring gene zinc finger protein 131 Neighboring gene NIM1 serine/threonine protein kinase Neighboring gene uncharacterized LOC107215781 Neighboring gene C-C motif chemokine ligand 28 Neighboring gene transmembrane protein 267

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables hydroxymethylglutaryl-CoA synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in acetyl-CoA metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in farnesyl diphosphate biosynthetic process, mevalonate pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hydroxymethylglutaryl-CoA synthase, cytoplasmic

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Parus major Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Parus_major1.1 Primary Assembly

Genomic

  1. NC_031799.1 Reference Parus_major1.1 Primary Assembly

    Range
    13510386..13521562 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015615043.2 → XP_015470529.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X2

    Related
    ENSPMJP00000021368.1, ENSPMJT00000027793.1
    Conserved Domains (3) summary
    TIGR01833
    Location:13 → 470
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:16 → 186
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:187 → 470
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal

  2. XM_015615042.3 → XP_015470528.1  hydroxymethylglutaryl-CoA synthase, cytoplasmic isoform X1

    Conserved Domains (3) summary
    TIGR01833
    Location:22 → 479
    HMG-CoA-S_euk; 3-hydroxy-3-methylglutaryl-CoA-synthase, eukaryotic clade
    pfam01154
    Location:25 → 195
    HMG_CoA_synt_N; Hydroxymethylglutaryl-coenzyme A synthase N terminal
    pfam08540
    Location:196 → 479
    HMG_CoA_synt_C; Hydroxymethylglutaryl-coenzyme A synthase C terminal
Nucleotide Protein
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