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epha4a eph receptor A4a [ Poecilia latipinna (sailfin molly) ]

Gene ID: 106935212, updated on 11-Apr-2024

Summary

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Gene symbol
epha4a
Gene description
eph receptor A4a
See related
Ensembl:ENSPLAG00000001289
Gene type
protein coding
RefSeq status
MODEL
Organism
Poecilia latipinna
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
Also known as
epha4
Orthologs
zebrafish all
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Genomic context

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See epha4a in Genome Data Viewer
Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
100 current P_latipinna-1.0 (GCF_001443285.1) Unplaced Scaffold NW_015114544.1 (37312..106906)

NW_015114544.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC106935213

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_015114544.1 Unplaced Scaffold Reference P_latipinna-1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane-ephrin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of axon extension IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ephrin type-A receptor 4
Names
EPH receptor A4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Poecilia latipinna Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P_latipinna-1.0

Genomic

  1. NW_015114544.1 Reference P_latipinna-1.0

    Range
    37312..106906
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_015015569.1 → XP_014871055.1  ephrin type-A receptor 4 isoform X1

    UniProtKB/TrEMBL
    A0A3B3V2K4
    Conserved Domains (9) summary
    cd09545
    Location:922 → 992
    SAM_EPH-A4; SAM domain of EPH-A4 subfamily of tyrosine kinase receptors
    smart00454
    Location:926 → 986
    SAM; Sterile alpha motif
    cd10482
    Location:32 → 205
    EphR_LBD_A4; Ligand Binding Domain of Ephrin type-A Receptor 4
    cd00063
    Location:442 → 533
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:617 → 891
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    cd00185
    Location:278 → 309
    TNFRSF; CRD2 [structural motif]
    pfam07714
    Location:622 → 887
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 617
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl22855
    Location:252 → 381
    TNFRSF; Tumor necrosis factor receptor superfamily (TNFRSF)

  2. XM_015015570.1 → XP_014871056.1  ephrin type-A receptor 4 isoform X2

    UniProtKB/TrEMBL
    A0A3B3V2K4
    Conserved Domains (7) summary
    cd09545
    Location:919 → 989
    SAM_EPH-A4; SAM domain of EPH-A4 subfamily of tyrosine kinase receptors
    smart00454
    Location:923 → 983
    SAM; Sterile alpha motif
    cd10482
    Location:32 → 205
    EphR_LBD_A4; Ligand Binding Domain of Ephrin type-A Receptor 4
    cd00063
    Location:442 → 533
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:617 → 888
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:622 → 884
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 617
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  3. XM_015015571.1 → XP_014871057.1  ephrin type-A receptor 4 isoform X3

    UniProtKB/TrEMBL
    A0A3B3V2K4
    Conserved Domains (7) summary
    cd09545
    Location:917 → 987
    SAM_EPH-A4; SAM domain of EPH-A4 subfamily of tyrosine kinase receptors
    smart00454
    Location:921 → 981
    SAM; Sterile alpha motif
    cd10482
    Location:32 → 205
    EphR_LBD_A4; Ligand Binding Domain of Ephrin type-A Receptor 4
    cd00063
    Location:442 → 533
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:617 → 886
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:622 → 882
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 617
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  4. XM_015015573.1 → XP_014871059.1  ephrin type-A receptor 4 isoform X4

    UniProtKB/TrEMBL
    A0A3B3V2K4
    Related
    ENSPLAP00000019283.1, ENSPLAT00000016404.1
    Conserved Domains (7) summary
    cd09545
    Location:914 → 984
    SAM_EPH-A4; SAM domain of EPH-A4 subfamily of tyrosine kinase receptors
    smart00454
    Location:918 → 978
    SAM; Sterile alpha motif
    cd10482
    Location:32 → 205
    EphR_LBD_A4; Ligand Binding Domain of Ephrin type-A Receptor 4
    cd00063
    Location:442 → 533
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:617 → 883
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:622 → 879
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 617
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
Nucleotide Protein
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