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ACAN aggrecan [ Equus asinus (ass) ]

Gene ID: 106832021, updated on 13-Mar-2024

Summary

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Gene symbol
ACAN
Gene description
aggrecan
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus asinus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
17
Annotation release Status Assembly Chr Location
101 current ASM1607732v2 (GCF_016077325.2) 2 NC_052178.1 (137523145..137559474, complement)
100 previous assembly ASM130575v1 (GCF_001305755.1) Unplaced Scaffold NW_014637754.1 (8744956..8807787)

Chromosome 2 - NC_052178.1Genomic Context describing neighboring genes Neighboring gene milk fat globule EGF and factor V/VIII domain containing Neighboring gene hyaluronan and proteoglycan link protein 3 Neighboring gene U6 spliceosomal RNA Neighboring gene interferon stimulated exonuclease gene 20

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables hyaluronic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
aggrecan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus asinus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1607732v2

Genomic

  1. NC_052178.1 Reference ASM1607732v2

    Range
    137523145..137559474 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_044744378.1 → XP_044600313.1  aggrecan core protein

    Conserved Domains (11) summary
    cd00033
    Location:2529 → 2585
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    cd03588
    Location:2402 → 2525
    CLECT_CSPGs; C-type lectin-like domain (CTLD) of the type found in chondroitin sulfate proteoglycan core proteins
    PRK14959
    Location:1855 → 2030
    PRK14959; DNA polymerase III subunits gamma and tau; Provisional
    PRK15319
    Location:786 → 1135
    PRK15319; fibronectin-binding autotransporter adhesin ShdA
    smart00406
    Location:39 → 128
    IGv; Immunoglobulin V-Type
    PHA03247
    Location:662 → 839
    PHA03247; large tegument protein UL36; Provisional
    PHA03307
    Location:1939 → 2372
    PHA03307; transcriptional regulator ICP4; Provisional
    cd00054
    Location:2360 → 2396
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd03517
    Location:146 → 240
    Link_domain_CSPGs_modules_1_3; this extracellular link domain is found in the first and third link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan. In addition, it is found in the first link module of three other CSPGs: versican, neurocan, and brevican. ...
    cd03520
    Location:247 → 342
    Link_domain_CSPGs_modules_2_4; this link domain is found in the second and fourth link modules of the chondroitin sulfate proteoglycan core protein (CSPG) aggrecan and, in the second link module of three other CSPGs: versican, neurocan, and brevican. The link domain is a hyaluronan ...
    cd00096
    Location:65 → 69
    Ig; Ig strand C [structural motif]
Nucleotide Protein
Heading Accession and Version

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