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hspg2 heparan sulfate proteoglycan 2 [ Fundulus heteroclitus (mummichog) ]

Gene ID: 105935210, updated on 20-Aug-2024

Summary

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Gene symbol
hspg2
Gene description
heparan sulfate proteoglycan 2
See related
EnsemblRapid:ENSFHEG00000007346
Gene type
protein coding
RefSeq status
MODEL
Organism
Fundulus heteroclitus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Fundulidae; Fundulus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 1
Exon count:
92
Annotation release Status Assembly Chr Location
102 current MU-UCD_Fhet_4.1 (GCF_011125445.2) 1 NC_046361.1 (34162653..34327783, complement)
101 previous assembly Fundulus_heteroclitus-3.0.2 (GCF_000826765.1) Unplaced Scaffold NW_012234419.1 (330959..487443)

Chromosome 1 - NC_046361.1Genomic Context describing neighboring genes Neighboring gene membrane associated guanylate kinase, WW and PDZ domain containing 3a Neighboring gene transmembrane protein 269 Neighboring gene uncharacterized LOC118564206 Neighboring gene tubulin alpha-1B chain Neighboring gene agmatinase (putative)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cell-cell adhesion mediator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in dendrite self-avoidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in homophilic cell adhesion via plasma membrane adhesion molecules IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in axon IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
basement membrane-specific heparan sulfate proteoglycan core protein
Names
Basement membrane-specific heparan sulfate proteoglycan core protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fundulus heteroclitus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference MU-UCD_Fhet_4.1 Primary Assembly

Genomic

  1. NC_046361.1 Reference MU-UCD_Fhet_4.1 Primary Assembly

    Range
    34162653..34327783 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_021323026.2 → XP_021178701.2  basement membrane-specific heparan sulfate proteoglycan core protein isoform X2

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (16) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00410
    Location:2581 → 2662
    IG_like; Immunoglobulin like
    cd00054
    Location:3297 → 3326
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3377 → 3528
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3553 → 3584
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2265 → 2377
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3022 → 3092
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2943 → 2947
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1963 → 2048
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2940 → 3018
    Ig; Immunoglobulin domain

  2. XM_021323024.2 → XP_021178699.2  basement membrane-specific heparan sulfate proteoglycan core protein isoform X14

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Related
    ENSFHEP00000046054.1, ENSFHET00000046994.1
    Conserved Domains (17) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2588 → 2664
    IG; Immunoglobulin
    smart00410
    Location:2490 → 2571
    IG_like; Immunoglobulin like
    cd00054
    Location:3206 → 3235
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3286 → 3437
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3462 → 3493
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2174 → 2286
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2931 → 3001
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2852 → 2856
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1964 → 2049
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2849 → 2927
    Ig; Immunoglobulin domain

  3. XM_036141530.1 → XP_035997423.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X3

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (16) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2582 → 2663
    IG; Immunoglobulin
    cd00054
    Location:3292 → 3321
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3372 → 3523
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3548 → 3579
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2266 → 2378
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3023 → 3093
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2944 → 2948
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1964 → 2049
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2941 → 3019
    Ig; Immunoglobulin domain

  4. XM_036141541.1 → XP_035997434.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X8

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (17) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2582 → 2663
    IG; Immunoglobulin
    smart00410
    Location:2680 → 2756
    IG_like; Immunoglobulin like
    cd00054
    Location:3298 → 3327
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3378 → 3529
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3554 → 3585
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2266 → 2378
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3023 → 3093
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2944 → 2948
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1964 → 2049
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2941 → 3019
    Ig; Immunoglobulin domain

  5. XM_036141523.1 → XP_035997416.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X1

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (16) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00410
    Location:2582 → 2663
    IG_like; Immunoglobulin like
    cd00054
    Location:3298 → 3327
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3378 → 3529
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3554 → 3585
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2266 → 2378
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3023 → 3093
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2944 → 2948
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1964 → 2049
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2941 → 3019
    Ig; Immunoglobulin domain

  6. XM_036141581.1 → XP_035997474.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X18

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Related
    ENSFHEP00000047207.1, ENSFHET00000048252.1
    Conserved Domains (17) summary
    cd05743
    Location:420 → 497
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2623 → 2699
    IG; Immunoglobulin
    smart00410
    Location:2525 → 2606
    IG_like; Immunoglobulin like
    cd00054
    Location:3241 → 3270
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1153 → 1202
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3321 → 3472
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:324 → 358
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3497 → 3528
    EGF; EGF-like domain
    pfam00052
    Location:1529 → 1665
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:876 → 918
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:284 → 318
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2209 → 2321
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2966 → 3036
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2887 → 2891
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1907 → 1992
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:82 → 193
    SEA; SEA domain
    cl11960
    Location:2884 → 2962
    Ig; Immunoglobulin domain

  7. XM_021323027.2 → XP_021178702.2  basement membrane-specific heparan sulfate proteoglycan core protein isoform X10

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (17) summary
    cd05743
    Location:420 → 497
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:1854 → 1934
    IG; Immunoglobulin
    smart00410
    Location:2560 → 2641
    IG_like; Immunoglobulin like
    cd00054
    Location:3276 → 3305
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1153 → 1202
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3356 → 3507
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:324 → 358
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3532 → 3563
    EGF; EGF-like domain
    pfam00052
    Location:1564 → 1700
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:876 → 918
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:284 → 318
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2244 → 2356
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3001 → 3071
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2922 → 2926
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1942 → 2027
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:82 → 193
    SEA; SEA domain
    cl11960
    Location:2919 → 2997
    Ig; Immunoglobulin domain

  8. XM_036141533.1 → XP_035997426.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X4

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (17) summary
    cd05743
    Location:429 → 506
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2569 → 2650
    IG; Immunoglobulin
    smart00410
    Location:1863 → 1943
    IG_like; Immunoglobulin like
    cd00054
    Location:3285 → 3314
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1162 → 1211
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3365 → 3516
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:333 → 367
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3541 → 3572
    EGF; EGF-like domain
    pfam00052
    Location:1573 → 1709
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:885 → 927
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:293 → 327
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2253 → 2365
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3010 → 3080
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2931 → 2935
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1951 → 2036
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2928 → 3006
    Ig; Immunoglobulin domain

  9. XM_036141556.1 → XP_035997449.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X13

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Related
    ENSFHEP00000043435.1, ENSFHET00000060261.1
    Conserved Domains (17) summary
    cd05743
    Location:400 → 477
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2540 → 2621
    IG; Immunoglobulin
    smart00410
    Location:1834 → 1914
    IG_like; Immunoglobulin like
    cd00054
    Location:3256 → 3285
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1133 → 1182
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3336 → 3487
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:304 → 338
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3512 → 3543
    EGF; EGF-like domain
    pfam00052
    Location:1544 → 1680
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:856 → 898
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:264 → 298
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2224 → 2336
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2981 → 3051
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2902 → 2906
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1922 → 2007
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2899 → 2977
    Ig; Immunoglobulin domain

  10. XM_036141534.1 → XP_035997427.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X5

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (16) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00410
    Location:2569 → 2650
    IG_like; Immunoglobulin like
    cd00054
    Location:3285 → 3314
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3365 → 3516
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3541 → 3572
    EGF; EGF-like domain
    pfam00052
    Location:1573 → 1709
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2253 → 2365
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3010 → 3080
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2931 → 2935
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1951 → 2036
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2928 → 3006
    Ig; Immunoglobulin domain

  11. XM_036141555.1 → XP_035997448.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X12

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Related
    ENSFHEP00000053404.1, ENSFHET00000050792.1
    Conserved Domains (16) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00410
    Location:2547 → 2628
    IG_like; Immunoglobulin like
    cd00054
    Location:3263 → 3292
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3343 → 3494
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3519 → 3550
    EGF; EGF-like domain
    pfam00052
    Location:1551 → 1687
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2231 → 2343
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2988 → 3058
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2909 → 2913
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1929 → 2014
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2906 → 2984
    Ig; Immunoglobulin domain

  12. XM_036141562.1 → XP_035997455.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X15

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (16) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2481 → 2562
    IG; Immunoglobulin
    cd00054
    Location:3197 → 3226
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3277 → 3428
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3453 → 3484
    EGF; EGF-like domain
    pfam00052
    Location:1485 → 1621
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2165 → 2277
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2922 → 2992
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2843 → 2847
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1863 → 1948
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2840 → 2918
    Ig; Immunoglobulin domain

  13. XM_036141538.1 → XP_035997431.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X7

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (17) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:1859 → 1939
    IG; Immunoglobulin
    smart00410
    Location:2565 → 2646
    IG_like; Immunoglobulin like
    cd00054
    Location:3281 → 3310
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3361 → 3512
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3537 → 3568
    EGF; EGF-like domain
    pfam00052
    Location:1569 → 1705
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2249 → 2361
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3006 → 3076
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2927 → 2931
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1947 → 2032
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2924 → 3002
    Ig; Immunoglobulin domain

  14. XM_036141543.1 → XP_035997436.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X9

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Related
    ENSFHEP00000057143.1, ENSFHET00000055363.1
    Conserved Domains (17) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2562 → 2643
    IG; Immunoglobulin
    smart00410
    Location:1876 → 1956
    IG_like; Immunoglobulin like
    cd00054
    Location:3278 → 3307
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3358 → 3509
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3534 → 3565
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2246 → 2358
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3003 → 3073
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2924 → 2928
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1964 → 2049
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2921 → 2999
    Ig; Immunoglobulin domain

  15. XM_036141552.1 → XP_035997445.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X11

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (17) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:2556 → 2637
    IG; Immunoglobulin
    smart00410
    Location:2654 → 2730
    IG_like; Immunoglobulin like
    cd00054
    Location:3272 → 3301
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3352 → 3503
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3528 → 3559
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2266 → 2352
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2997 → 3067
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2283 → 2287
    Ig; Ig strand B [structural motif]
    cd05754
    Location:1964 → 2049
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2915 → 2993
    Ig; Immunoglobulin domain

  16. XM_036141584.1 → XP_035997477.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X19

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (16) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00410
    Location:2582 → 2663
    IG_like; Immunoglobulin like
    cd00054
    Location:3292 → 3321
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3372 → 3523
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3548 → 3579
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2266 → 2378
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3023 → 3093
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2944 → 2948
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1964 → 2049
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2941 → 3019
    Ig; Immunoglobulin domain

  17. XM_036141535.1 → XP_035997428.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X6

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (16) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00410
    Location:2582 → 2663
    IG_like; Immunoglobulin like
    cd00054
    Location:3298 → 3327
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3378 → 3529
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3554 → 3585
    EGF; EGF-like domain
    pfam00052
    Location:1586 → 1722
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2266 → 2378
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:3023 → 3093
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2944 → 2948
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1964 → 2049
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2941 → 3019
    Ig; Immunoglobulin domain

  18. XM_036141575.1 → XP_035997468.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X17

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Related
    ENSFHEP00000056528.1, ENSFHET00000069164.1
    Conserved Domains (17) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:1699 → 1779
    IG; Immunoglobulin
    smart00410
    Location:2405 → 2486
    IG_like; Immunoglobulin like
    cd00054
    Location:3121 → 3150
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1219
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3201 → 3352
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3377 → 3408
    EGF; EGF-like domain
    pfam00052
    Location:1409 → 1545
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2089 → 2201
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2846 → 2916
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2767 → 2771
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1787 → 1872
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2764 → 2842
    Ig; Immunoglobulin domain

  19. XM_036141572.1 → XP_035997465.1  basement membrane-specific heparan sulfate proteoglycan core protein isoform X16

    UniProtKB/TrEMBL
    A0A3Q2QD42
    Conserved Domains (17) summary
    cd05743
    Location:442 → 519
    Ig_Perlecan_like; Immunoglobulin (Ig)-like domain of the human basement membrane heparan sulfate proteoglycan perlecan and similar proteins
    smart00409
    Location:1727 → 1807
    IG; Immunoglobulin
    smart00410
    Location:2433 → 2514
    IG_like; Immunoglobulin like
    cd00054
    Location:3149 → 3178
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    cd00055
    Location:1175 → 1224
    EGF_Lam; Laminin-type epidermal growth factor-like domain; laminins are the major noncollagenous components of basement membranes that mediate cell adhesion, growth migration, and differentiation; the laminin-type epidermal growth factor-like module occurs in ...
    cd00110
    Location:3229 → 3380
    LamG; Laminin G domain; Laminin G-like domains are usually Ca++ mediated receptors that can have binding sites for steroids, beta1 integrins, heparin, sulfatides, fibulin-1, and alpha-dystroglycans. Proteins that contain LamG domains serve a variety of ...
    cd00112
    Location:346 → 380
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00008
    Location:3405 → 3436
    EGF; EGF-like domain
    pfam00052
    Location:1437 → 1573
    Laminin_B; Laminin B (Domain IV)
    pfam00053
    Location:898 → 940
    Laminin_EGF; Laminin EGF domain
    pfam00057
    Location:306 → 340
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam07679
    Location:2117 → 2229
    I-set; Immunoglobulin I-set domain
    pfam13927
    Location:2874 → 2944
    Ig_3; Immunoglobulin domain
    cd00096
    Location:2795 → 2799
    Ig; Ig strand A' [structural motif]
    cd05754
    Location:1815 → 1900
    IgI_Perlecan_like; Immunoglobulin (Ig)-like domain found in Perlecan and similar proteins; member of the I-set of Ig superfamily (IgSF) domains
    cl02507
    Location:109 → 215
    SEA; SEA domain
    cl11960
    Location:2792 → 2870
    Ig; Immunoglobulin domain
Nucleotide Protein
Heading Accession and Version

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