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twnk twinkle mtDNA helicase [ Clupea harengus (Atlantic herring) ]

Gene ID: 105894050, updated on 18-Jun-2024

Summary

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Gene symbol
twnk
Gene description
twinkle mtDNA helicase
See related
Ensembl:ENSCHAG00020025632
Gene type
protein coding
RefSeq status
MODEL
Organism
Clupea harengus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Clupei; Clupeiformes; Clupeoidei; Clupeidae; Clupea
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 23
Exon count:
6
Annotation release Status Assembly Chr Location
102 current Ch_v2.0.2 (GCF_900700415.2) 23 NC_045174.1 (19927895..19933508)

Chromosome 23 - NC_045174.1Genomic Context describing neighboring genes Neighboring gene DPY30 domain containing 2 Neighboring gene mitochondrial ribosomal protein L43 Neighboring gene leucine zipper, putative tumor suppressor 2b Neighboring gene PDZ domain-containing protein 7 Neighboring gene peroxiredoxin-like 2A

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_045174.1 Chromosome 23 Reference Ch_v2.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-3' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables single-stranded DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitochondrial DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: twinkle protein, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Clupea harengus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Ch_v2.0.2 Primary Assembly

Genomic

  1. NC_045174.1 Reference Ch_v2.0.2 Primary Assembly

    Range
    19927895..19933508
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012820524.3 → XP_012675978.2  LOW QUALITY PROTEIN: twinkle protein, mitochondrial

    UniProtKB/TrEMBL
    A0A6P3VMK0
    Related
    ENSCHAP00020058911.1, ENSCHAT00020063370.1
    Conserved Domains (2) summary
    cd01029
    Location:299 → 375
    TOPRIM_primases; The topoisomerase-primase (TORPIM) nucleotidyl transferase/hydrolase domain found in the active site regions of bacterial DnaG-type primases and their homologs. Primases synthesize RNA primers for the initiation of DNA replication. DnaG type primases are ...
    cd01122
    Location:414 → 671
    GP4d_helicase; GP4d_helicase is a homohexameric 5'-3' helicases. Helicases couple NTP hydrolysis to the unwinding of nucleic acid duplexes into their component strands.
Nucleotide Protein
Heading Accession and Version

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