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RFFL ring finger and FYVE like domain containing E3 ubiquitin protein ligase [ Propithecus coquereli (Coquerel's sifaka) ]

Gene ID: 105813866, updated on 13-Mar-2024

Summary

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Gene symbol
RFFL
Gene description
ring finger and FYVE like domain containing E3 ubiquitin protein ligase
See related
Ensembl:ENSPCOG00000014273
Gene type
protein coding
RefSeq status
MODEL
Organism
Propithecus coquereli
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Strepsirrhini; Lemuriformes; Indriidae; Propithecus
Orthologs
human mouse all
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Genomic context

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See RFFL in Genome Data Viewer
Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
100 current Pcoq_1.0 (GCF_000956105.1) Unplaced Scaffold NW_012148519.1 (276204..338625, complement)

NW_012148519.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 830 Neighboring gene DNA ligase 3 Neighboring gene RAD51 paralog D Neighboring gene fibronectin type III domain containing 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012148519.1 Unplaced Scaffold Reference Pcoq_1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of cysteine-type endopeptidase activity involved in execution phase of apoptosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of extrinsic apoptotic signaling pathway via death domain receptors IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteasome-mediated ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K48-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase rififylin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Propithecus coquereli Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Pcoq_1.0 Primary Assembly

Genomic

  1. NW_012148519.1 Reference Pcoq_1.0 Primary Assembly

    Range
    276204..338625 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012648674.1 → XP_012504128.1  E3 ubiquitin-protein ligase rififylin isoform X2

    UniProtKB/TrEMBL
    A0A2K6EX18, A0A2K6EX56
    Related
    ENSPCOP00000006278.1, ENSPCOT00000016803.1
    Conserved Domains (2) summary
    cd15770
    Location:44 → 92
    FYVE_CARP2; FYVE-like domain found in caspase regulator CARP2 and similar proteins
    pfam13920
    Location:311 → 355
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)

  2. XM_012648673.1 → XP_012504127.1  E3 ubiquitin-protein ligase rififylin isoform X1

    UniProtKB/TrEMBL
    A0A2K6EX18
    Conserved Domains (2) summary
    cd15770
    Location:79 → 127
    FYVE_CARP2; FYVE-like domain found in caspase regulator CARP2 and similar proteins
    pfam13920
    Location:346 → 390
    zf-C3HC4_3; Zinc finger, C3HC4 type (RING finger)
Nucleotide Protein
Heading Accession and Version

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