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RASGEF1A RasGEF domain family member 1A [ Aotus nancymaae (Ma's night monkey) ]

Gene ID: 105734328, updated on 6-Jun-2024

Summary

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Gene symbol
RASGEF1A
Gene description
RasGEF domain family member 1A
See related
Ensembl:ENSANAG00000022560
Gene type
protein coding
RefSeq status
MODEL
Organism
Aotus nancymaae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Platyrrhini; Aotidae; Aotus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
17
Annotation release Status Assembly Chr Location
RS_2024_04 current 86718_ANA_hifiasm-v0.15.2.pri (GCF_030222135.1) Unplaced Scaffold NW_026988514.1 (3972081..4043148)
101 previous assembly Anan_2.0 (GCF_000952055.2) Unplaced Scaffold NW_018499839.1 (445924..481002)

NW_026988514.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC135271947 Neighboring gene U6atac minor spliceosomal RNA Neighboring gene chondroitin sulfate N-acetylgalactosaminyltransferase 2 Neighboring gene proto-oncogene tyrosine-protein kinase receptor Ret Neighboring gene proto-oncogene tyrosine-protein kinase receptor Ret-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Ras protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras-GEF domain-containing family member 1A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_030222135.1-RS_2024_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

Genomic

  1. NW_026988514.1 Reference 86718_ANA_hifiasm-v0.15.2.pri Primary Assembly

    Range
    3972081..4043148
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_064370075.1 → XP_064226145.1  ras-GEF domain-containing family member 1A isoform X2

    UniProtKB/TrEMBL
    A0A2K5CKI0

  2. XM_012477107.3 → XP_012332530.1  ras-GEF domain-containing family member 1A isoform X2

    See identical proteins and their annotated locations for XP_012332530.1

    UniProtKB/TrEMBL
    A0A2K5CKI0
    Conserved Domains (2) summary
    cd06224
    Location:49 → 176
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00147
    Location:214 → 462
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

  3. XM_012477104.2 → XP_012332527.1  ras-GEF domain-containing family member 1A isoform X1

    UniProtKB/TrEMBL
    A0A2K5CK87, A0A2K5CKB0
    Related
    ENSANAP00000009155.1
    Conserved Domains (2) summary
    cd06224
    Location:57 → 184
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00147
    Location:222 → 470
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

  4. XM_012477106.3 → XP_012332529.1  ras-GEF domain-containing family member 1A isoform X2

    See identical proteins and their annotated locations for XP_012332529.1

    UniProtKB/TrEMBL
    A0A2K5CKI0
    Related
    ENSANAP00000009161.1
    Conserved Domains (2) summary
    cd06224
    Location:49 → 176
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00147
    Location:214 → 462
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases

  5. XM_012477105.3 → XP_012332528.1  ras-GEF domain-containing family member 1A isoform X2

    See identical proteins and their annotated locations for XP_012332528.1

    UniProtKB/TrEMBL
    A0A2K5CKI0
    Conserved Domains (2) summary
    cd06224
    Location:49 → 176
    REM; Guanine nucleotide exchange factor for Ras-like GTPases; N-terminal domain (RasGef_N), also called REM domain (Ras exchanger motif). This domain is common in nucleotide exchange factors for Ras-like small GTPases and is typically found immediately ...
    smart00147
    Location:214 → 462
    RasGEF; Guanine nucleotide exchange factor for Ras-like small GTPases
Nucleotide Protein
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