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DCLRE1B DNA cross-link repair 1B [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105596356, updated on 13-Mar-2024

Summary

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Gene symbol
DCLRE1B
Gene description
DNA cross-link repair 1B
See related
Ensembl:ENSCATG00000015222
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012001927.1 (3119507..3128168, complement)

NW_012001927.1Genomic Context describing neighboring genes Neighboring gene olfactomedin like 3 Neighboring gene homeodomain interacting protein kinase 1 Neighboring gene adaptor related protein complex 4 subunit beta 1 Neighboring gene BCL2 like 15 Neighboring gene protein tyrosine phosphatase non-receptor type 22

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012001927.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-3' DNA exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables damaged DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in double-strand break repair via nonhomologous end joining IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in interstrand cross-link repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protection from non-homologous end joining at telomere IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
5' exonuclease Apollo

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012001927.1 Reference Caty_1.0

    Range
    3119507..3128168 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012083310.1 → XP_011938700.1  5' exonuclease Apollo isoform X1

    UniProtKB/TrEMBL
    A0A2K5KUA2
    Related
    ENSCATP00000004258.1, ENSCATT00000017338.1
    Conserved Domains (3) summary
    cd11662
    Location:496 → 529
    apollo_TRF2_binding; TRF2-binding region of apollo and similar proteins
    pfam07522
    Location:216 → 299
    DRMBL; DNA repair metallo-beta-lactamase
    cd16273
    Location:6 → 151
    SNM1A-1C-like_MBL-fold; SNM1A , artemis/SNM1C, yeast Pso2p, and related proteins; MBL-fold metallo-hydrolase domain

  2. XM_012083312.1 → XP_011938702.1  5' exonuclease Apollo isoform X2

    See identical proteins and their annotated locations for XP_011938702.1

    Conserved Domains (3) summary
    cd11662
    Location:407 → 440
    apollo_TRF2_binding; TRF2-binding region of apollo and similar proteins
    pfam07522
    Location:127 → 210
    DRMBL; DNA repair metallo-beta-lactamase
    cl23716
    Location:2 → 62
    metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain

  3. XM_012083311.1 → XP_011938701.1  5' exonuclease Apollo isoform X2

    See identical proteins and their annotated locations for XP_011938701.1

    Conserved Domains (3) summary
    cd11662
    Location:407 → 440
    apollo_TRF2_binding; TRF2-binding region of apollo and similar proteins
    pfam07522
    Location:127 → 210
    DRMBL; DNA repair metallo-beta-lactamase
    cl23716
    Location:2 → 62
    metallo-hydrolase-like_MBL-fold; mainly hydrolytic enzymes and related proteins which carry out various biological functions; MBL-fold metallohydrolase domain
Nucleotide Protein
Heading Accession and Version

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