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EPHA5 EPH receptor A5 [ Cercocebus atys (sooty mangabey) ]

Gene ID: 105596081, updated on 11-Apr-2024

Summary

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Gene symbol
EPHA5
Gene description
EPH receptor A5
See related
Ensembl:ENSCATG00000035595
Gene type
protein coding
RefSeq status
MODEL
Organism
Cercocebus atys
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Cercocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
100 current Caty_1.0 (GCF_000955945.1) Unplaced Scaffold NW_012001851.1 (491009..833215, complement)

NW_012001851.1Genomic Context describing neighboring genes Neighboring gene 40S ribosomal protein S2 pseudogene Neighboring gene centromere protein C

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012001851.1 Unplaced Scaffold Reference Caty_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane-ephrin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ephrin type-A receptor 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cercocebus atys Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Caty_1.0

Genomic

  1. NW_012001851.1 Reference Caty_1.0

    Range
    491009..833215 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_012082723.1 → XP_011938113.1  ephrin type-A receptor 5 isoform X7

    UniProtKB/TrEMBL
    A0A2K5MGE5
    Related
    ENSCATP00000024258.1, ENSCATT00000048482.1
    Conserved Domains (7) summary
    cd09546
    Location:802 → 867
    SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
    smart00454
    Location:806 → 864
    SAM; Sterile alpha motif
    cd10483
    Location:60 → 232
    EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
    cd00063
    Location:305 → 395
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:507 → 773
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:512 → 769
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:415 → 507
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  2. XM_012082721.1 → XP_011938111.1  ephrin type-A receptor 5 isoform X5

    UniProtKB/TrEMBL
    A0A2K5MGB5
    Related
    ENSCATP00000024252.1, ENSCATT00000048476.1
    Conserved Domains (7) summary
    cd09546
    Location:854 → 919
    SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
    smart00454
    Location:858 → 916
    SAM; Sterile alpha motif
    cd10483
    Location:60 → 232
    EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
    cd00063
    Location:357 → 447
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:559 → 825
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:564 → 821
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:467 → 559
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  3. XM_012082720.1 → XP_011938110.1  ephrin type-A receptor 5 isoform X4

    Conserved Domains (7) summary
    cd09546
    Location:943 → 1008
    SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
    smart00454
    Location:947 → 1005
    SAM; Sterile alpha motif
    cd10483
    Location:60 → 232
    EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
    cd00063
    Location:469 → 559
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:648 → 914
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:653 → 910
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:578 → 648
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  4. XM_012082718.1 → XP_011938108.1  ephrin type-A receptor 5 isoform X2

    Conserved Domains (7) summary
    cd09546
    Location:965 → 1030
    SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
    smart00454
    Location:969 → 1027
    SAM; Sterile alpha motif
    cd10483
    Location:60 → 232
    EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
    cd00063
    Location:469 → 559
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:670 → 936
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:675 → 932
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:578 → 670
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  5. XM_012082719.1 → XP_011938109.1  ephrin type-A receptor 5 isoform X3

    UniProtKB/TrEMBL
    A0A2K5MGF3
    Related
    ENSCATP00000024249.1, ENSCATT00000048473.1
    Conserved Domains (7) summary
    cd09546
    Location:944 → 1009
    SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
    smart00454
    Location:948 → 1006
    SAM; Sterile alpha motif
    cd10483
    Location:60 → 232
    EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
    cd00063
    Location:469 → 559
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:649 → 915
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:654 → 911
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:579 → 649
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  6. XM_012082717.1 → XP_011938107.1  ephrin type-A receptor 5 isoform X1

    UniProtKB/TrEMBL
    A0A2K5MGB6
    Related
    ENSCATP00000024246.1, ENSCATT00000048470.1
    Conserved Domains (7) summary
    cd09546
    Location:966 → 1031
    SAM_EPH-A5; SAM domain of EPH-A5 subfamily of tyrosine kinase receptors
    smart00454
    Location:970 → 1028
    SAM; Sterile alpha motif
    cd10483
    Location:60 → 232
    EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
    cd00063
    Location:469 → 559
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:671 → 937
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:676 → 933
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:579 → 671
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain

  7. XM_012082722.1 → XP_011938112.1  ephrin type-A receptor 5 isoform X6

    Conserved Domains (6) summary
    cd10483
    Location:60 → 232
    EphR_LBD_A5; Ligand Binding Domain of Ephrin type-A Receptor 5
    cd00063
    Location:357 → 447
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:558 → 824
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:563 → 820
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:466 → 558
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:853 → 891
    SAM_superfamily; SAM (Sterile alpha motif )
Nucleotide Protein
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