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SMG7 SMG7 nonsense mediated mRNA decay factor [ Mandrillus leucophaeus (drill) ]

Gene ID: 105550425, updated on 13-Mar-2024

Summary

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Gene symbol
SMG7
Gene description
SMG7 nonsense mediated mRNA decay factor
See related
Ensembl:ENSMLEG00000037170
Gene type
protein coding
RefSeq status
MODEL
Organism
Mandrillus leucophaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Mandrillus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current Mleu.le_1.0 (GCF_000951045.1) Unplaced Scaffold NW_012105187.1 (1134204..1228335)

NW_012105187.1Genomic Context describing neighboring genes Neighboring gene laminin subunit gamma 2 Neighboring gene nicotinamide nucleotide adenylyltransferase 2 Neighboring gene neutrophil cytosolic factor 2 Neighboring gene actin related protein 2/3 complex subunit 5

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012105187.1 Unplaced Scaffold Reference Mleu.le_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomerase RNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables telomeric DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nuclear-transcribed mRNA catabolic process, nonsense-mediated decay IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of telomerase holoenzyme complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein SMG7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Mandrillus leucophaeus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mleu.le_1.0

Genomic

  1. NW_012105187.1 Reference Mleu.le_1.0

    Range
    1134204..1228335
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011995336.1 → XP_011850726.1  protein SMG7 isoform X1

    See identical proteins and their annotated locations for XP_011850726.1

    Related
    ENSMLEP00000026256.1, ENSMLET00000049792.1
    Conserved Domains (3) summary
    sd00006
    Location:154 → 180
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:171 → 431
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:55 → 167
    EST1; Telomerase activating protein Est1

  2. XM_011995339.1 → XP_011850729.1  protein SMG7 isoform X4

    See identical proteins and their annotated locations for XP_011850729.1

    UniProtKB/TrEMBL
    A0A2K5ZEM0
    Related
    ENSMLEP00000026233.1, ENSMLET00000049768.1
    Conserved Domains (3) summary
    sd00006
    Location:154 → 180
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:171 → 431
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:55 → 167
    EST1; Telomerase activating protein Est1

  3. XM_011995337.1 → XP_011850727.1  protein SMG7 isoform X2

    Conserved Domains (3) summary
    sd00006
    Location:154 → 180
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:171 → 431
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:55 → 167
    EST1; Telomerase activating protein Est1

  4. XM_011995340.1 → XP_011850730.1  protein SMG7 isoform X5

    See identical proteins and their annotated locations for XP_011850730.1

    Conserved Domains (3) summary
    sd00006
    Location:154 → 180
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:171 → 431
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:55 → 167
    EST1; Telomerase activating protein Est1

  5. XM_011995338.1 → XP_011850728.1  protein SMG7 isoform X3

    See identical proteins and their annotated locations for XP_011850728.1

    UniProtKB/TrEMBL
    A0A2K5ZEL0
    Related
    ENSMLEP00000026223.1, ENSMLET00000049758.1
    Conserved Domains (3) summary
    sd00006
    Location:112 → 138
    TPR; TPR repeat [structural motif]
    pfam10373
    Location:129 → 389
    EST1_DNA_bind; Est1 DNA/RNA binding domain
    pfam10374
    Location:13 → 125
    EST1; Telomerase activating protein Est1
Nucleotide Protein
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