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GMPR2 guanosine monophosphate reductase 2 [ Macaca nemestrina (pig-tailed macaque) ]

Gene ID: 105477857, updated on 13-Mar-2024

Summary

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Gene symbol
GMPR2
Gene description
guanosine monophosphate reductase 2
See related
Ensembl:ENSMNEG00000039387
Gene type
protein coding
RefSeq status
MODEL
Organism
Macaca nemestrina
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Macaca
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current Mnem_1.0 (GCF_000956065.1) Unplaced Scaffold NW_012017132.1 (559131..566247)

NW_012017132.1Genomic Context describing neighboring genes Neighboring gene importin 4 Neighboring gene transmembrane 9 superfamily member 1 Neighboring gene magnesium-dependent phosphatase 1 Neighboring gene testis specific serine kinase 4 Neighboring gene NEDD8 ubiquitin like modifier Neighboring gene TERF1 interacting nuclear factor 2 Neighboring gene transglutaminase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_012017132 Unplaced Scaffold Reference Mnem_1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GMP reductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in nucleotide metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of GMP reductase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
GMP reductase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Macaca nemestrina Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Mnem_1.0

Genomic

  1. NW_012017132.1 Reference Mnem_1.0

    Range
    559131..566247
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024791559.1 → XP_024647327.1  GMP reductase 2 isoform X4

    Conserved Domains (1) summary
    cl27608
    Location:33 → 309
    IMPDH; IMP dehydrogenase / GMP reductase domain

  2. XM_011734703.2 → XP_011733005.1  GMP reductase 2 isoform X4

    See identical proteins and their annotated locations for XP_011733005.1

    Conserved Domains (1) summary
    cl27608
    Location:33 → 309
    IMPDH; IMP dehydrogenase / GMP reductase domain

  3. XM_011734700.2 → XP_011733002.1  GMP reductase 2 isoform X2

    See identical proteins and their annotated locations for XP_011733002.1

    UniProtKB/TrEMBL
    A0A2K6D7X7, A0A2K6D7Z9
    Conserved Domains (2) summary
    PRK05096
    Location:3 → 345
    PRK05096; guanosine 5'-monophosphate oxidoreductase; Provisional
    cd00381
    Location:10 → 336
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...

  4. XM_011734698.2 → XP_011733000.1  GMP reductase 2 isoform X2

    See identical proteins and their annotated locations for XP_011733000.1

    UniProtKB/TrEMBL
    A0A2K6D7X7, A0A2K6D7Z9
    Related
    ENSMNEP00000032018.1, ENSMNET00000056451.1
    Conserved Domains (2) summary
    PRK05096
    Location:3 → 345
    PRK05096; guanosine 5'-monophosphate oxidoreductase; Provisional
    cd00381
    Location:10 → 336
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...

  5. XM_011734699.1 → XP_011733001.1  GMP reductase 2 isoform X2

    See identical proteins and their annotated locations for XP_011733001.1

    UniProtKB/TrEMBL
    A0A2K6D7X7, A0A2K6D7Z9
    Conserved Domains (2) summary
    PRK05096
    Location:3 → 345
    PRK05096; guanosine 5'-monophosphate oxidoreductase; Provisional
    cd00381
    Location:10 → 336
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...

  6. XM_011734704.2 → XP_011733006.1  GMP reductase 2 isoform X4

    See identical proteins and their annotated locations for XP_011733006.1

    Conserved Domains (1) summary
    cl27608
    Location:33 → 309
    IMPDH; IMP dehydrogenase / GMP reductase domain

  7. XM_011734697.1 → XP_011732999.1  GMP reductase 2 isoform X1

    UniProtKB/TrEMBL
    A0A2K6D7Z9
    Related
    ENSMNEP00000032036.1, ENSMNET00000056469.1
    Conserved Domains (2) summary
    PRK05096
    Location:21 → 363
    PRK05096; guanosine 5'-monophosphate oxidoreductase; Provisional
    cd00381
    Location:28 → 354
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...

  8. XM_011734702.1 → XP_011733004.1  GMP reductase 2 isoform X3

    UniProtKB/TrEMBL
    A0A2K6D7Z9
    Conserved Domains (1) summary
    cd00381
    Location:28 → 298
    IMPDH; IMPDH: The catalytic domain of the inosine monophosphate dehydrogenase. IMPDH catalyzes the NAD-dependent oxidation of inosine 5'-monophosphate (IMP) to xanthosine 5' monophosphate (XMP). It is a rate-limiting step in the de novo synthesis of the guanine ...
Nucleotide Protein
Heading Accession and Version

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