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C1R complement C1r [ Bison bison bison ]

Gene ID: 104992161, updated on 12-Mar-2024

Summary

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Gene symbol
C1R
Gene description
complement C1r
See related
Ensembl:ENSBBBG00000013692
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
human all
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Genomic context

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Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011494785.1 (39526..52563)

NW_011494785.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104992160 Neighboring gene complement C1s Neighboring gene lysophosphatidylcholine acyltransferase 3 Neighboring gene EMG1 N1-specific pseudouridine methyltransferase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011494785.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in zymogen activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in blood microparticle IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
complement C1r subcomponent

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011494785.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    39526..52563
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010844915.1 → XP_010843217.1  complement C1r subcomponent

    UniProtKB/TrEMBL
    A0A6P3HV91
    Related
    ENSBBBP00000004796.1, ENSBBBT00000007422.1
    Conserved Domains (6) summary
    smart00020
    Location:434 → 668
    Tryp_SPc; Trypsin-like serine protease
    smart00042
    Location:2 → 109
    CUB; Domain first found in C1r, C1s, uEGF, and bone morphogenetic protein
    cd00190
    Location:435 → 671
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:280 → 342
    Sushi; Sushi repeat (SCR repeat)
    pfam00431
    Location:164 → 273
    CUB; CUB domain
    pfam14670
    Location:132 → 160
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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