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LRP1 LDL receptor related protein 1 [ Bison bison bison ]

Gene ID: 104988158, updated on 12-Mar-2024

Summary

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Gene symbol
LRP1
Gene description
LDL receptor related protein 1
See related
Ensembl:ENSBBBG00000012523
Gene type
protein coding
RefSeq status
MODEL
Organism
Bison bison bison (sub-species: bison)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae; Bovinae; Bison
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
88
Annotation release Status Assembly Chr Location
100 current Bison_UMD1.0 (GCF_000754665.1) Unplaced Scaffold NW_011494687.1 (1670486..1752636)

NW_011494687.1Genomic Context describing neighboring genes Neighboring gene NGFI-A binding protein 2 Neighboring gene signal transducer and activator of transcription 6 Neighboring gene neurexophilin 4 Neighboring gene serine hydroxymethyltransferase 2 Neighboring gene NDUFA4 mitochondrial complex associated like 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_011494687.1 Unplaced Scaffold Reference Bison_UMD1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: prolow-density lipoprotein receptor-related protein 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Bison bison bison Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Bison_UMD1.0 Primary Assembly

Genomic

  1. NW_011494687.1 Reference Bison_UMD1.0 Primary Assembly

    Range
    1670486..1752636
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010839371.1 → XP_010837673.1  LOW QUALITY PROTEIN: prolow-density lipoprotein receptor-related protein 1

    UniProtKB/TrEMBL
    A0A6P3H2B5
    Related
    ENSBBBP00000003411.1, ENSBBBT00000010032.1
    Conserved Domains (9) summary
    smart00192
    Location:3367 → 3400
    LDLa; Low-density lipoprotein receptor domain class A
    smart00135
    Location:3088 → 3130
    LY; Low-density lipoprotein-receptor YWTD domain
    COG3386
    Location:2253 → 2463
    YvrE; Sugar lactone lactonase YvrE [Carbohydrate transport and metabolism]
    cd00112
    Location:3449 → 3483
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    pfam00057
    Location:2856 → 2890
    Ldl_recept_a; Low-density lipoprotein receptor domain class A
    pfam00058
    Location:3887 → 3927
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    pfam12662
    Location:2961 → 2984
    cEGF; Complement Clr-like EGF-like
    pfam14670
    Location:807 → 842
    FXa_inhibition; Coagulation Factor Xa inhibitory site
    cl00104
    Location:71 → 104
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
Nucleotide Protein
Heading Accession and Version

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