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ptpn13 protein tyrosine phosphatase non-receptor type 13 [ Notothenia coriiceps (black rockcod) ]

Gene ID: 104954540, updated on 12-Mar-2024

Summary

Gene symbol
ptpn13
Gene description
protein tyrosine phosphatase non-receptor type 13
Gene type
protein coding
RefSeq status
MODEL
Organism
Notothenia coriiceps
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Eupercaria; Perciformes; Notothenioidei; Nototheniidae; Notothenia
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
49
Annotation release Status Assembly Chr Location
100 current NC01 (GCF_000735185.1) Unplaced Scaffold NW_011356221.1 (230915..558025)

NW_011356221.1Genomic Context describing neighboring genes Neighboring gene nuclear factor 1-like Neighboring gene mitogen-activated protein kinase 10 Neighboring gene uncharacterized LOC104954539 Neighboring gene cdc42 effector protein 4-like Neighboring gene sidekick cell adhesion molecule 2 Neighboring gene SDA1 domain containing 1 Neighboring gene kelch-like family member 8

Genomic regions, transcripts, and products

Genomic Sequence:
NW_011356221.1 Unplaced Scaffold Reference NC01 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol 3-kinase regulatory subunit binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein tyrosine phosphatase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
tyrosine-protein phosphatase non-receptor type 13

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Notothenia coriiceps Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference NC01 Primary Assembly

Genomic

  1. NW_011356221.1 Reference NC01 Primary Assembly

    Range
    230915..558025
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010781657.1XP_010779959.1  tyrosine-protein phosphatase non-receptor type 13 isoform X1

    UniProtKB/TrEMBL
    A0A6I9NQC8
    Conserved Domains (10) summary
    smart00194
    Location:23122563
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:13881480
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:592796
    B41; Band 4.1 homologues
    cd00047
    Location:23362563
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:11141198
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:683796
    FERM_M; FERM central domain
    pfam09379
    Location:592654
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:11991390
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:792892
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:3177
    PKc_like; Protein Kinases, catalytic domain
  2. XM_010781659.1XP_010779961.1  tyrosine-protein phosphatase non-receptor type 13 isoform X3

    UniProtKB/TrEMBL
    A0A6I9P079
    Conserved Domains (10) summary
    smart00194
    Location:23072558
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:13881475
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:592796
    B41; Band 4.1 homologues
    cd00047
    Location:23312558
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:11141198
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:683796
    FERM_M; FERM central domain
    pfam09379
    Location:592654
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:11991390
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:792892
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:3177
    PKc_like; Protein Kinases, catalytic domain
  3. XM_010781660.1XP_010779962.1  tyrosine-protein phosphatase non-receptor type 13 isoform X4

    UniProtKB/TrEMBL
    A0A6I9NV32
    Conserved Domains (10) summary
    smart00194
    Location:22682519
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:14851575
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:592796
    B41; Band 4.1 homologues
    cd00047
    Location:22922519
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:11141198
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:683796
    FERM_M; FERM central domain
    pfam09379
    Location:592654
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:11991368
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:792892
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:3177
    PKc_like; Protein Kinases, catalytic domain
  4. XM_010781658.1XP_010779960.1  tyrosine-protein phosphatase non-receptor type 13 isoform X2

    UniProtKB/TrEMBL
    A0A6I9NY10
    Conserved Domains (10) summary
    smart00194
    Location:23112562
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00228
    Location:13871479
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    smart00295
    Location:591795
    B41; Band 4.1 homologues
    cd00047
    Location:23352562
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00992
    Location:11131197
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    pfam00373
    Location:682795
    FERM_M; FERM central domain
    pfam09379
    Location:591653
    FERM_N; FERM N-terminal domain
    pfam16599
    Location:11981389
    PTN13_u3; Unstructured linker region on PTN13 protein between PDZ
    cl17171
    Location:791891
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:3177
    PKc_like; Protein Kinases, catalytic domain