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Tmtc2 transmembrane O-mannosyltransferase targeting cadherins 2 [ Fukomys damarensis (Damara mole-rat) ]

Gene ID: 104852473, updated on 12-Mar-2024

Summary

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Gene symbol
Tmtc2
Gene description
transmembrane O-mannosyltransferase targeting cadherins 2
Locus tag
H920_01773
See related
Ensembl:ENSFDAG00000004009
Gene type
protein coding
RefSeq status
MODEL
Organism
Fukomys damarensis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Hystricomorpha; Bathyergidae; Fukomys
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
102 current DMR_v1.0_HiC (GCF_012274545.1) Unplaced Scaffold NW_022900927.1 (45666155..46050910)
101 previous assembly DMR_v1.0 (GCF_000743615.1) Unplaced Scaffold NW_011043842.1 (797523..1182278)

NW_022900927.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC104852454 Neighboring gene Y-box-binding protein 1-like Neighboring gene uncharacterized LOC104852488 Neighboring gene thymidylate synthase-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables mannosyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein O-linked mannosylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in endoplasmic reticulum membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
protein O-mannosyl-transferase TMTC2
Names
Transmembrane and TPR repeat-containing protein 2
transmembrane and tetratricopeptide repeat containing 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Fukomys damarensis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference DMR_v1.0_HiC Primary Assembly

Genomic

  1. NW_022900927.1 Reference DMR_v1.0_HiC Primary Assembly

    Range
    45666155..46050910
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010610162.1 → XP_010608464.1  protein O-mannosyl-transferase TMTC2 isoform X1

    UniProtKB/TrEMBL
    A0A091E0G4
    Related
    ENSFDAP00000015852.1, ENSFDAT00000006330.1
    Conserved Domains (7) summary
    sd00006
    Location:527 → 555
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:779 → 812
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:609 → 638
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:247 → 321
    DUF1736; Domain of unknown function (DUF1736)
    pfam13414
    Location:493 → 554
    TPR_11; TPR repeat
    pfam13424
    Location:557 → 634
    TPR_12; Tetratricopeptide repeat
    pfam14559
    Location:755 → 822
    TPR_19; Tetratricopeptide repeat

  2. XM_010610177.2 → XP_010608479.1  protein O-mannosyl-transferase TMTC2 isoform X5

    UniProtKB/TrEMBL
    A0A091E0G4
    Conserved Domains (6) summary
    sd00006
    Location:527 → 555
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:493 → 520
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:609 → 638
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:247 → 321
    DUF1736; Domain of unknown function (DUF1736)
    pfam13414
    Location:493 → 554
    TPR_11; TPR repeat
    pfam13424
    Location:557 → 634
    TPR_12; Tetratricopeptide repeat

  3. XM_033763823.1 → XP_033619714.1  protein O-mannosyl-transferase TMTC2 isoform X4

    UniProtKB/TrEMBL
    A0A091E0G4
    Conserved Domains (3) summary
    COG0457
    Location:481 → 712
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:527 → 555
    TPR; TPR repeat [structural motif]
    pfam08409
    Location:248 → 321
    DUF1736; Domain of unknown function (DUF1736)

  4. XM_010610171.3 → XP_010608473.1  protein O-mannosyl-transferase TMTC2 isoform X3

    UniProtKB/TrEMBL
    A0A091E0G4
    Conserved Domains (6) summary
    TIGR02795
    Location:471 → 551
    tol_pal_ybgF; tol-pal system protein YbgF
    COG0457
    Location:512 → 789
    TPR; Tetratricopeptide (TPR) repeat [General function prediction only]
    sd00006
    Location:527 → 555
    TPR; TPR repeat [structural motif]
    pfam00515
    Location:493 → 520
    TPR_1; Tetratricopeptide repeat
    pfam07719
    Location:609 → 638
    TPR_2; Tetratricopeptide repeat
    pfam08409
    Location:247 → 321
    DUF1736; Domain of unknown function (DUF1736)

  5. XM_019205476.1 → XP_019061021.1  protein O-mannosyl-transferase TMTC2 isoform X2

    UniProtKB/TrEMBL
    A0A091E0G4
Nucleotide Protein
Heading Accession and Version

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