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BCR BCR activator of RhoGEF and GTPase [ Balearica regulorum gibbericeps (East African grey crowned-crane) ]

Gene ID: 104642779, updated on 3-Aug-2024

Summary

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Gene symbol
BCR
Gene description
BCR activator of RhoGEF and GTPase
Locus tag
N312_11284
Gene type
protein coding
RefSeq status
MODEL
Organism
Balearica regulorum gibbericeps (sub-species: gibbericeps)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Gruiformes; Gruidae; Balearica
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
25
Annotation release Status Assembly Chr Location
100 current ASM70989v1 (GCF_000709895.1) Unplaced Scaffold NW_010737534.1 (10114..108910, complement)

NW_010737534.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_010737534.1 Unplaced Scaffold Reference ASM70989v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breakpoint cluster region protein
Names
BCR, RhoGEF and GTPase activating protein
Breakpoint cluster region protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Balearica regulorum gibbericeps Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM70989v1 Primary Assembly

Genomic

  1. NW_010737534.1 Reference ASM70989v1 Primary Assembly

    Range
    10114..108910 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_010311868.1 → XP_010310170.1  breakpoint cluster region protein isoform X1

    UniProtKB/TrEMBL
    A0A087V4L3
    Conserved Domains (5) summary
    cd08686
    Location:993 → 1113
    C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
    cd04387
    Location:1132 → 1332
    RhoGAP_Bcr; RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, ...
    pfam00621
    Location:582 → 770
    RhoGEF; RhoGEF domain
    pfam09036
    Location:3 → 75
    Bcr-Abl_Oligo; Bcr-Abl oncoprotein oligomerization domain
    cl17171
    Location:764 → 957
    PH-like; Pleckstrin homology-like domain

  2. XM_010311869.1 → XP_010310171.1  breakpoint cluster region protein isoform X2

    Conserved Domains (4) summary
    cd08686
    Location:462 → 582
    C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
    cd04387
    Location:601 → 801
    RhoGAP_Bcr; RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, ...
    cd13367
    Location:233 → 426
    PH_BCR_vertebrate; Breakpoint Cluster Region-related pleckstrin homology (PH) domain
    pfam00621
    Location:51 → 239
    RhoGEF; RhoGEF domain
Nucleotide Protein
Heading Accession and Version

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