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BCR BCR activator of RhoGEF and GTPase [ Opisthocomus hoazin ]

Gene ID: 104328213, updated on 3-Aug-2024

Summary

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Gene symbol
BCR
Gene description
BCR activator of RhoGEF and GTPase
Locus tag
N306_04876
Gene type
protein coding
RefSeq status
MODEL
Organism
Opisthocomus hoazin
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Opisthocomiformes; Opisthocomidae; Opisthocomus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current ASM69207v1 (GCF_000692075.1) Unplaced Scaffold NW_009900824.1 (147004..248398)

NW_009900824.1Genomic Context describing neighboring genes Neighboring gene radial spoke head 14 homolog Neighboring gene G protein subunit alpha z Neighboring gene RAB36, member RAS oncogene family Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 like Neighboring gene adenosine A2a receptor

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009900824.1 Unplaced Scaffold Reference ASM69207v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breakpoint cluster region protein
Names
BCR, RhoGEF and GTPase activating protein
Breakpoint cluster region protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Opisthocomus hoazin Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69207v1

Genomic

  1. NW_009900824.1 Reference ASM69207v1

    Range
    147004..248398
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009933201.1 → XP_009931503.1  breakpoint cluster region protein

    UniProtKB/TrEMBL
    A0A091W480
    Conserved Domains (5) summary
    cd08686
    Location:993 → 1113
    C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
    cd04387
    Location:1132 → 1332
    RhoGAP_Bcr; RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, ...
    pfam00621
    Location:582 → 770
    RhoGEF; RhoGEF domain
    pfam09036
    Location:3 → 75
    Bcr-Abl_Oligo; Bcr-Abl oncoprotein oligomerization domain
    cl17171
    Location:764 → 957
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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