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MCL1 MCL1 apoptosis regulator, BCL2 family member [ Egretta garzetta (little egret) ]

Gene ID: 104134875, updated on 12-Mar-2024

Summary

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Gene symbol
MCL1
Gene description
MCL1 apoptosis regulator, BCL2 family member
Locus tag
Z169_02046
Gene type
protein coding
RefSeq status
MODEL
Organism
Egretta garzetta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Pelecaniformes; Ardeidae; Egretta
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
101 current ASM68718v1 (GCF_000687185.1) Unplaced Scaffold NW_009258664.1 (358872..361884)

NW_009258664.1Genomic Context describing neighboring genes Neighboring gene HORMA domain containing 1 Neighboring gene golgi phosphoprotein 3 like Neighboring gene endosulfine alpha

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009258664 Unplaced Scaffold Reference ASM68718v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables channel activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein heterodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in extrinsic apoptotic signaling pathway in absence of ligand IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intrinsic apoptotic signaling pathway in response to DNA damage IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitochondrial fusion IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in release of cytochrome c from mitochondria IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrial outer membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
induced myeloid leukemia cell differentiation protein Mcl-1
Names
BCL2 family apoptosis regulator
Induced myeloid leukemia cell differentiation protein Mcl-1
MCL1, BCL2 family apoptosis regulator

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Egretta garzetta Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM68718v1 Primary Assembly

Genomic

  1. NW_009258664.1 Reference ASM68718v1 Primary Assembly

    Range
    358872..361884
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009648465.2 → XP_009646760.1  induced myeloid leukemia cell differentiation protein Mcl-1

    UniProtKB/TrEMBL
    A0A091IR22
    Conserved Domains (1) summary
    cd06845
    Location:22 → 103
    Bcl-2_like; Apoptosis regulator proteins of the Bcl-2 family, named after B-cell lymphoma 2. This alignment model spans what have been described as Bcl-2 homology regions BH1, BH2, BH3, and BH4. Many members of this family have an additional C-terminal transmembrane ...
Nucleotide Protein
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