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MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [ Egretta garzetta (little egret) ]

Gene ID: 104130378, updated on 3-Aug-2024

Summary

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Gene symbol
MTHFD2
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Locus tag
Z169_05243
Gene type
protein coding
RefSeq status
MODEL
Organism
Egretta garzetta
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Pelecaniformes; Ardeidae; Egretta
Orthologs
human mouse all
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Genomic context

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See MTHFD2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
101 current ASM68718v1 (GCF_000687185.1) Unplaced Scaffold NW_009260402.1 (753165..768094)

NW_009260402.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC118452767 Neighboring gene MOB kinase activator 1A Neighboring gene solute carrier family 4 member 5 Neighboring gene electrogenic sodium bicarbonate cotransporter 1-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009260402 Unplaced Scaffold Reference ASM68718v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methenyltetrahydrofolate cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Egretta garzetta Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM68718v1 Primary Assembly

Genomic

  1. NW_009260402.1 Reference ASM68718v1 Primary Assembly

    Range
    753165..768094
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009643414.2 → XP_009641709.1  bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

    UniProtKB/TrEMBL
    A0A091JGL8
    Conserved Domains (3) summary
    cd01080
    Location:120 → 299
    NAD_bind_m-THF_DH_Cyclohyd; NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
    COG0190
    Location:9 → 300
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
    pfam00763
    Location:9 → 125
    THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
Nucleotide Protein
Heading Accession and Version

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