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PAPPA pappalysin 1 [ Pelecanus crispus (Dalmatian pelican) ]

Gene ID: 104030865, updated on 3-Aug-2024

Summary

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Gene symbol
PAPPA
Gene description
pappalysin 1
Locus tag
N334_05908
Gene type
protein coding
RefSeq status
MODEL
Organism
Pelecanus crispus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Pelecaniformes; Pelecanidae; Pelecanus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
100 current ASM68737v1 (GCF_000687375.1) Unplaced Scaffold NW_009084890.1 (36761..214793)

NW_009084890.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_009084890.1 Unplaced Scaffold Reference ASM68737v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metallopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pappalysin-1
Names
Pappalysin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pelecanus crispus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM68737v1

Genomic

  1. NW_009084890.1 Reference ASM68737v1

    Range
    36761..214793
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009482689.1 → XP_009480964.1  pappalysin-1

    UniProtKB/TrEMBL
    A0A091SR24
    Conserved Domains (6) summary
    cd00033
    Location:1296 → 1343
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00004
    Location:1547 → 1583
    NL; Domain found in Notch and Lin-12
    TIGR02232
    Location:943 → 982
    myxo_disulf_rpt; Myxococcus cysteine-rich repeat
    smart00560
    Location:111 → 259
    LamGL; LamG-like jellyroll fold domain
    cd04275
    Location:420 → 656
    ZnMc_pappalysin_like; Zinc-dependent metalloprotease, pappalysin_like subfamily. The pregnancy-associated plasma protein A (PAPP-A or pappalysin-1) cleaves insulin-like growth factor-binding proteins 4 and 5, thereby promoting cell growth by releasing bound growth factor. ...
    pfam00084
    Location:1415 → 1471
    Sushi; Sushi repeat (SCR repeat)
Nucleotide Protein
Heading Accession and Version

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