U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

MTHFD2 methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase [ Pygoscelis adeliae (Adelie penguin) ]

Gene ID: 103917169, updated on 3-Aug-2024

Summary

Go to the top of the page Help
Gene symbol
MTHFD2
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2, methenyltetrahydrofolate cyclohydrolase
Locus tag
AS28_12221
Gene type
protein coding
RefSeq status
MODEL
Organism
Pygoscelis adeliae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Neoaves; Aequornithes; Sphenisciformes; Spheniscidae; Pygoscelis
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
100 current ASM69910v1 (GCF_000699105.1) Unplaced Scaffold NW_008824821.1 (189770..199694, complement)

NW_008824821.1Genomic Context describing neighboring genes Neighboring gene tetraspanin-15-like Neighboring gene solute carrier family 4 member 5 Neighboring gene MOB kinase activator 1A

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_008824821.1 Unplaced Scaffold Reference ASM69910v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methenyltetrahydrofolate cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Pygoscelis adeliae Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69910v1 Primary Assembly

Genomic

  1. NW_008824821.1 Reference ASM69910v1 Primary Assembly

    Range
    189770..199694 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009324278.1 → XP_009322553.1  bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase, mitochondrial

    UniProtKB/TrEMBL
    A0A093R8F4
    Conserved Domains (3) summary
    cd01080
    Location:135 → 314
    NAD_bind_m-THF_DH_Cyclohyd; NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
    COG0190
    Location:24 → 315
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
    pfam00763
    Location:24 → 140
    THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.