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Mtmr4 myotubularin related protein 4 [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103741780, updated on 11-Mar-2024

Summary

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Gene symbol
Mtmr4
Gene description
myotubularin related protein 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
20
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008346261.1 (3256520..3283017)

NW_008346261.1Genomic Context describing neighboring genes Neighboring gene testis expressed 14, intercellular bridge forming factor Neighboring gene small nucleolar RNA SNORA40 Neighboring gene septin 4 Neighboring gene heat shock transcription factor 5 Neighboring gene ring finger protein 43

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008346261 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. Malik A, et al. PLoS One, 2011. PMID 21857902, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables metal ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-3,5-bisphosphate 3-phosphatase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein phosphatase binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dephosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of autophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
myotubularin-related protein 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008346261.1 Reference S.galili_v1.0 Primary Assembly

    Range
    3256520..3283017
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029568097.1 → XP_029423957.1  myotubularin-related protein 4 isoform X2

    Conserved Domains (3) summary
    cd13342
    Location:23 → 136
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1107 → 1166
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    cd14587
    Location:172 → 479
    PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

  2. XM_029568098.1 → XP_029423958.1  myotubularin-related protein 4 isoform X2

    Conserved Domains (3) summary
    cd13342
    Location:23 → 136
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1107 → 1166
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    cd14587
    Location:172 → 479
    PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

  3. XM_008842690.3 → XP_008840912.1  myotubularin-related protein 4 isoform X2

    Conserved Domains (3) summary
    cd13342
    Location:23 → 136
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1107 → 1166
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    cd14587
    Location:172 → 479
    PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

  4. XM_029568099.1 → XP_029423959.1  myotubularin-related protein 4 isoform X3

    Conserved Domains (2) summary
    cd13342
    Location:37 → 150
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd14587
    Location:186 → 493
    PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4

  5. XM_008842689.3 → XP_008840911.1  myotubularin-related protein 4 isoform X1

    Conserved Domains (3) summary
    cd13342
    Location:37 → 150
    PH-GRAM_MTMR4; Myotubularian (MTM) related 4 protein (MTMR4) Pleckstrin Homology-Glucosyltransferases, Rab-like GTPase activators and Myotubularins (PH-GRAM) domain
    cd15733
    Location:1121 → 1180
    FYVE_MTMR4; FYVE domain found in myotubularin-related protein 4 (MTMR4) and similar proteins
    cd14587
    Location:186 → 493
    PTP-MTMR4; protein tyrosine phosphatase-like domain of myotubularin related phosphoinositide phosphatase 4
Nucleotide Protein
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