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DFFA DNA fragmentation factor subunit alpha [ Ursus maritimus (polar bear) ]

Gene ID: 103666870, updated on 11-Mar-2024

Summary

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Gene symbol
DFFA
Gene description
DNA fragmentation factor subunit alpha
See related
Ensembl:ENSUMAG00000023754
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
6
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024425786.1 (7569548..7577344, complement)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907138.1 (22226695..22234563)

NW_024425786.1Genomic Context describing neighboring genes Neighboring gene centromere protein S-like Neighboring gene cortistatin-like Neighboring gene U6 spliceosomal RNA Neighboring gene peroxisomal biogenesis factor 14 Neighboring gene castor zinc finger 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables deoxyribonuclease inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in apoptotic DNA fragmentation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of apoptotic process IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
DNA fragmentation factor subunit alpha

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024425786.1 Reference ASM1731132v1 Primary Assembly

    Range
    7569548..7577344 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008694951.2 → XP_008693173.2  DNA fragmentation factor subunit alpha

    UniProtKB/TrEMBL
    A0A384CE79, A0A452VH32
    Conserved Domains (2) summary
    pfam09033
    Location:96 → 260
    DFF-C; DNA Fragmentation factor 45kDa, C terminal domain
    cl02541
    Location:14 → 92
    CIDE_N; CIDE_N domain, found at the N-terminus of the CIDE (cell death-inducing DFF45-like effector) proteins, as well as CAD nuclease (caspase-activated DNase/DNA fragmentation factor, DFF40) and its inhibitor, ICAD(DFF45). These proteins are associated with ...
Nucleotide Protein
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