U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

WRN WRN RecQ like helicase [ Galeopterus variegatus (Sunda flying lemur) ]

Gene ID: 103601083, updated on 11-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
WRN
Gene description
WRN RecQ like helicase
Gene type
protein coding
RefSeq status
MODEL
Organism
Galeopterus variegatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Dermoptera; Cynocephalidae; Galeopterus
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
34
Annotation release Status Assembly Chr Location
100 current G_variegatus-3.0.2 (GCF_000696425.1) Unplaced Scaffold NW_007729692.1 (71638..208226)

NW_007729692.1Genomic Context describing neighboring genes Neighboring gene purine rich element binding protein G

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_007729692 unplaced scaffold reference G_variegatus-3.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3'-5' DNA helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 3'-5' exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables four-way junction helicase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleic acid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables nucleotide binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in DNA unwinding involved in DNA replication IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in G-quadruplex DNA unwinding IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
Werner syndrome ATP-dependent helicase
Names
Werner syndrome RecQ like helicase

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Galeopterus variegatus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference G_variegatus-3.0.2 Primary Assembly

Genomic

  1. NW_007729692.1 Reference G_variegatus-3.0.2 Primary Assembly

    Range
    71638..208226
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008585463.1 → XP_008583685.1  Werner syndrome ATP-dependent helicase

    Conserved Domains (7) summary
    smart00341
    Location:1075 → 1153
    HRDC; Helicase and RNase D C-terminal
    TIGR00614
    Location:522 → 933
    recQ_fam; ATP-dependent DNA helicase, RecQ family
    cd06129
    Location:61 → 229
    RNaseD_like; DEDDy 3'-5' exonuclease domain of RNase D, WRN, and similar proteins
    smart00956
    Location:881 → 974
    RQC; This DNA-binding domain is found in the RecQ helicase among others and has a helix-turn-helix structure
    cd00079
    Location:669 → 790
    HELICc; Helicase superfamily c-terminal domain; associated with DEXDc-, DEAD-, and DEAH-box proteins, yeast initiation factor 4A, Ski2p, and Hepatitis C virus NS3 helicases; this domain is found in a wide variety of helicases and helicase related proteins; may ...
    pfam14493
    Location:1183 → 1273
    HTH_40; Helix-turn-helix domain
    pfam16124
    Location:795 → 862
    RecQ_Zn_bind; RecQ zinc-binding
Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.