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HIF1A hypoxia inducible factor 1 subunit alpha [ Equus przewalskii (Przewalski's horse) ]

Gene ID: 103562790, updated on 11-Mar-2024

Summary

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Gene symbol
HIF1A
Gene description
hypoxia inducible factor 1 subunit alpha
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus przewalskii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Annotation information
Annotation category: partial on reference assembly
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current Burgud (GCF_000696695.1) Unplaced Scaffold NW_007675648.1 (55254..97264)

NW_007675648.1Genomic Context describing neighboring genes Neighboring gene small nuclear RNA activating complex polypeptide 1 Neighboring gene uncharacterized LOC103562791

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007675648 unplaced scaffold reference Burgud Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II transcription regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to hypoxia IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
hypoxia-inducible factor 1-alpha
Names
hypoxia inducible factor 1 alpha subunit

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus przewalskii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Burgud Primary Assembly

Genomic

  1. NW_007675648.1 Reference Burgud Primary Assembly

    Range
    55254..97264
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008537924.1 → XP_008536146.1  hypoxia-inducible factor 1-alpha

    Conserved Domains (6) summary
    smart00091
    Location:99 → 154
    PAS; PAS domain
    cd00083
    Location:21 → 74
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    cd00130
    Location:245 → 344
    PAS; PAS domain; PAS motifs appear in archaea, eubacteria and eukarya. Probably the most surprising identification of a PAS domain was that in EAG-like K+-channels. PAS domains have been found to bind ligands, and to act as sensors for light and oxygen in ...
    pfam08447
    Location:260 → 345
    PAS_3; PAS fold
    pfam08778
    Location:792 → 828
    HIF-1a_CTAD; HIF-1 alpha C terminal transactivation domain
    pfam11413
    Location:557 → 584
    HIF-1; Hypoxia-inducible factor-1
Nucleotide Protein
Heading Accession and Version

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