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ect2 epithelial cell transforming 2 [ Poecilia reticulata (guppy) ]

Gene ID: 103464031, updated on 11-Mar-2024

Summary

Gene symbol
ect2
Gene description
epithelial cell transforming 2
See related
Ensembl:ENSPREG00000012918
Gene type
protein coding
RefSeq status
MODEL
Organism
Poecilia reticulata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
Orthologs
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Genomic context

See ect2 in Genome Data Viewer
Location:
chromosome: LG4
Exon count:
27
Annotation release Status Assembly LG Location
101 current Guppy_female_1.0+MT (GCF_000633615.1) LG4 NC_024334.1 (13263238..13314711)

Linkage Group LG4 - NC_024334.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103464036 Neighboring gene MCF.2 cell line derived transforming sequence-like 2 Neighboring gene UDP-GlcNAc:betaGal beta-1,3-N-acetylglucosaminyltransferase 5a Neighboring gene uncharacterized LOC103464029 Neighboring gene neuroligin 1 Neighboring gene uncharacterized LOC103464028 Neighboring gene N-acetylated alpha-linked acidic dipeptidase like 2

Genomic regions, transcripts, and products

Genomic Sequence:
NC_024334.1 Chromosome LG4 Reference Guppy_female_1.0+MT Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in activation of GTPase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in mitotic cytokinesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of cytokinesis, actomyosin contractile ring assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cell cortex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Poecilia reticulata Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Guppy_female_1.0+MT Primary Assembly

Genomic

  1. NC_024334.1 Reference Guppy_female_1.0+MT Primary Assembly

    Range
    13263238..13314711
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008407831.1XP_008406053.1  protein ECT2 isoform X5

    UniProtKB/TrEMBL
    A0A3P9PBB6
    Related
    ENSPREP00000019099.1, ENSPRET00000019305.1
    Conserved Domains (4) summary
    cd01229
    Location:682855
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:267342
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:507691
    RhoGEF; RhoGEF domain
    pfam12738
    Location:180243
    PTCB-BRCT; twin BRCT domain
  2. XM_008407826.1XP_008406048.1  protein ECT2 isoform X1

    UniProtKB/TrEMBL
    A0A3P9PBE5
    Related
    ENSPREP00000019129.1, ENSPRET00000019335.1
    Conserved Domains (4) summary
    cd01229
    Location:682855
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:267342
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:507691
    RhoGEF; RhoGEF domain
    pfam12738
    Location:180243
    PTCB-BRCT; twin BRCT domain
  3. XM_008407827.1XP_008406049.1  protein ECT2 isoform X2

    Conserved Domains (4) summary
    cd01229
    Location:681854
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:267342
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:506690
    RhoGEF; RhoGEF domain
    pfam12738
    Location:180243
    PTCB-BRCT; twin BRCT domain
  4. XM_008407829.1XP_008406051.1  protein ECT2 isoform X4

    UniProtKB/TrEMBL
    A0A3P9PBZ6
    Related
    ENSPREP00000019218.1, ENSPRET00000019424.1
    Conserved Domains (4) summary
    cd01229
    Location:629802
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:267342
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:454638
    RhoGEF; RhoGEF domain
    pfam12738
    Location:180243
    PTCB-BRCT; twin BRCT domain
  5. XM_008407828.1XP_008406050.1  protein ECT2 isoform X3

    UniProtKB/TrEMBL
    A0A3P9PB81
    Related
    ENSPREP00000019171.1, ENSPRET00000019377.1
    Conserved Domains (4) summary
    cd01229
    Location:651824
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:236311
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:476660
    RhoGEF; RhoGEF domain
    pfam12738
    Location:149212
    PTCB-BRCT; twin BRCT domain
  6. XM_008407832.2XP_008406054.1  protein ECT2 isoform X6

    Conserved Domains (4) summary
    cd01229
    Location:682855
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:267342
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:507691
    RhoGEF; RhoGEF domain
    pfam12738
    Location:180243
    PTCB-BRCT; twin BRCT domain
  7. XM_008407833.2XP_008406055.1  protein ECT2 isoform X7

    Conserved Domains (4) summary
    cd01229
    Location:598771
    PH_Ect2; Epithelial cell transforming 2 (Ect2) pleckstrin homology (PH) domain
    pfam00533
    Location:236311
    BRCT; BRCA1 C Terminus (BRCT) domain
    pfam00621
    Location:423607
    RhoGEF; RhoGEF domain
    pfam12738
    Location:149212
    PTCB-BRCT; twin BRCT domain