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ephb3 EPH receptor B3 [ Poecilia reticulata (guppy) ]

Gene ID: 103463460, updated on 11-Apr-2024

Summary

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Gene symbol
ephb3
Gene description
EPH receptor B3
See related
Ensembl:ENSPREG00000007218
Gene type
protein coding
RefSeq status
MODEL
Organism
Poecilia reticulata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
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Genomic context

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Location:
chromosome: LG4
Exon count:
16
Annotation release Status Assembly LG Location
101 current Guppy_female_1.0+MT (GCF_000633615.1) LG4 NC_024334.1 (6762675..6828598)

Linkage Group LG4 - NC_024334.1Genomic Context describing neighboring genes Neighboring gene hydroxylysine kinase, tandem duplicate 2 Neighboring gene uncharacterized LOC103463463 Neighboring gene uncharacterized LOC108166212 Neighboring gene major facilitator superfamily domain containing 8-like 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024334.1 Chromosome LG4 Reference Guppy_female_1.0+MT Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane-ephrin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ephrin type-B receptor 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Poecilia reticulata Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Guppy_female_1.0+MT Primary Assembly

Genomic

  1. NC_024334.1 Reference Guppy_female_1.0+MT Primary Assembly

    Range
    6762675..6828598
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008406819.2 → XP_008405041.1  ephrin type-B receptor 3 isoform X8

    UniProtKB/TrEMBL
    A0A3P9NM03
    Related
    ENSPREP00000010616.1, ENSPRET00000010740.1
    Conserved Domains (7) summary
    cd05065
    Location:613 → 921
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:654 → 917
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 613
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:923 → 967
    SAM_superfamily; SAM (Sterile alpha motif )

  2. XM_017304457.1 → XP_017159946.1  ephrin type-B receptor 3 isoform X2

    UniProtKB/TrEMBL
    A0A3P9NM03
    Conserved Domains (8) summary
    cd05065
    Location:609 → 917
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    smart00454
    Location:945 → 1012
    SAM; Sterile alpha motif
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:650 → 913
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 609
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:945 → 1013
    SAM_superfamily; SAM (Sterile alpha motif )

  3. XM_008406815.2 → XP_008405037.1  ephrin type-B receptor 3 isoform X1

    UniProtKB/TrEMBL
    A0A3P9NM03
    Conserved Domains (8) summary
    cd05065
    Location:613 → 921
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    smart00454
    Location:949 → 1016
    SAM; Sterile alpha motif
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:654 → 917
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 613
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:949 → 1017
    SAM_superfamily; SAM (Sterile alpha motif )

  4. XM_008406817.2 → XP_008405039.1  ephrin type-B receptor 3 isoform X4

    UniProtKB/TrEMBL
    A0A3P9NM03
    Conserved Domains (8) summary
    cd05065
    Location:613 → 893
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    smart00454
    Location:921 → 988
    SAM; Sterile alpha motif
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:618 → 889
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 613
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:921 → 989
    SAM_superfamily; SAM (Sterile alpha motif )

  5. XM_017304458.1 → XP_017159947.1  ephrin type-B receptor 3 isoform X5

    UniProtKB/TrEMBL
    A0A3P9NM03
    Conserved Domains (8) summary
    cd05065
    Location:609 → 889
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    smart00454
    Location:917 → 984
    SAM; Sterile alpha motif
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:614 → 885
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 609
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:917 → 985
    SAM_superfamily; SAM (Sterile alpha motif )

  6. XM_017304460.1 → XP_017159949.1  ephrin type-B receptor 3 isoform X9

    UniProtKB/TrEMBL
    A0A3P9NM03
    Conserved Domains (7) summary
    cd05065
    Location:609 → 877
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:614 → 873
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 609
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:879 → 923
    SAM_superfamily; SAM (Sterile alpha motif )

  7. XM_008406816.2 → XP_008405038.1  ephrin type-B receptor 3 isoform X3

    See identical proteins and their annotated locations for XP_008405038.1

    UniProtKB/TrEMBL
    A0A3P9NLZ3, A0A3P9NM03
    Related
    ENSPREP00000010606.1, ENSPRET00000010731.1
    Conserved Domains (8) summary
    cd05065
    Location:613 → 909
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    smart00454
    Location:937 → 1004
    SAM; Sterile alpha motif
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:654 → 905
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 613
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:937 → 1005
    SAM_superfamily; SAM (Sterile alpha motif )

  8. XM_017304459.1 → XP_017159948.1  ephrin type-B receptor 3 isoform X7

    UniProtKB/TrEMBL
    A0A3P9NM03
    Conserved Domains (8) summary
    cd05065
    Location:609 → 877
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    smart00454
    Location:905 → 972
    SAM; Sterile alpha motif
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:614 → 873
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 609
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:905 → 973
    SAM_superfamily; SAM (Sterile alpha motif )

  9. XM_008406818.2 → XP_008405040.1  ephrin type-B receptor 3 isoform X6

    See identical proteins and their annotated locations for XP_008405040.1

    UniProtKB/TrEMBL
    A0A3P9NM03
    Conserved Domains (8) summary
    cd05065
    Location:613 → 881
    PTKc_EphR_B; Catalytic domain of the Protein Tyrosine Kinases, Class EphB Ephrin Receptors
    smart00454
    Location:909 → 976
    SAM; Sterile alpha motif
    cd10478
    Location:21 → 193
    EphR_LBD_B3; Ligand Binding Domain of Ephrin type-B Receptor 3
    cd00063
    Location:433 → 524
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam00041
    Location:323 → 416
    fn3; Fibronectin type III domain
    pfam07714
    Location:618 → 877
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:562 → 613
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl15755
    Location:909 → 977
    SAM_superfamily; SAM (Sterile alpha motif )
Nucleotide Protein
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