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jak2a Janus kinase 2a [ Cynoglossus semilaevis (tongue sole) ]

Gene ID: 103389123, updated on 11-Apr-2024

Summary

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Gene symbol
jak2a
Gene description
Janus kinase 2a
See related
Ensembl:ENSCSEG00000017489
Gene type
protein coding
RefSeq status
MODEL
Organism
Cynoglossus semilaevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
Also known as
jak2
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: 14
Exon count:
24
Annotation release Status Assembly Chr Location
102 current Cse_v1.0 (GCF_000523025.1) 14 NC_024320.1 (2684635..2709276)

Chromosome 14 - NC_024320.1Genomic Context describing neighboring genes Neighboring gene roquin-2-like Neighboring gene ring finger and CCCH-type domains 2 Neighboring gene plasminogen receptor, C-terminal lysine transmembrane protein Neighboring gene relaxin 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024320.1 Chromosome 14 Reference Cse_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in hemopoiesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in peptidyl-tyrosine phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase JAK2
Names
Janus kinase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cse_v1.0 Primary Assembly

Genomic

  1. NC_024320.1 Reference Cse_v1.0 Primary Assembly

    Range
    2684635..2709276
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008324401.3 → XP_008322623.1  tyrosine-protein kinase JAK2

    UniProtKB/TrEMBL
    A0A3P8WKX7
    Related
    ENSCSEP00000027404.1, ENSCSET00000027772.1
    Conserved Domains (6) summary
    smart00219
    Location:846 → 1119
    TyrKc; Tyrosine kinase, catalytic domain
    smart00295
    Location:43 → 279
    B41; Band 4.1 homologues
    pfam07714
    Location:543 → 803
    Pkinase_Tyr; Protein tyrosine kinase
    cl15255
    Location:386 → 482
    SH2; Src homology 2 (SH2) domain
    cl17171
    Location:275 → 386
    PH-like; Pleckstrin homology-like domain
    cl21453
    Location:841 → 1124
    PKc_like; Protein Kinases, catalytic domain
Nucleotide Protein
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