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pcsk1 proprotein convertase subtilisin/kexin type 1 [ Cynoglossus semilaevis (tongue sole) ]

Gene ID: 103386425, updated on 11-Mar-2024

Summary

Gene symbol
pcsk1
Gene description
proprotein convertase subtilisin/kexin type 1
See related
Ensembl:ENSCSEG00000012536
Gene type
protein coding
RefSeq status
MODEL
Organism
Cynoglossus semilaevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
Orthologs
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Genomic context

Location:
chromosome: 11
Exon count:
14
Annotation release Status Assembly Chr Location
102 current Cse_v1.0 (GCF_000523025.1) 11 NC_024317.1 (13087843..13099717, complement)

Chromosome 11 - NC_024317.1Genomic Context describing neighboring genes Neighboring gene elongation factor for RNA polymerase II 2 Neighboring gene globoside alpha-1,3-N-acetylgalactosaminyltransferase 1-like Neighboring gene calpastatin Neighboring gene CD8a molecule

Genomic regions, transcripts, and products

Genomic Sequence:
NC_024317.1 Chromosome 11 Reference Cse_v1.0 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in protein processing IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in Golgi membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in trans-Golgi network IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
neuroendocrine convertase 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cse_v1.0 Primary Assembly

Genomic

  1. NC_024317.1 Reference Cse_v1.0 Primary Assembly

    Range
    13087843..13099717 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008320677.3XP_008318899.1  neuroendocrine convertase 1

    UniProtKB/TrEMBL
    A0A3P8VZE9, A0A3P8W545
    Related
    ENSCSEP00000019665.1, ENSCSET00000019904.1
    Conserved Domains (5) summary
    cd04059
    Location:136430
    Peptidases_S8_Protein_convertases_Kexins_Furin-like; Peptidase S8 family domain in Protein convertases
    pfam00082
    Location:173447
    Peptidase_S8; Subtilase family
    pfam01483
    Location:519606
    P_proprotein; Proprotein convertase P-domain
    pfam12177
    Location:745781
    Proho_convert; Prohormone convertase enzyme
    pfam16470
    Location:45121
    S8_pro-domain; Peptidase S8 pro-domain