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ATR ATR serine/threonine kinase [ Chlorocebus sabaeus (green monkey) ]

Gene ID: 103241557, updated on 11-Mar-2024

Summary

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Gene symbol
ATR
Gene description
ATR serine/threonine kinase
See related
Ensembl:ENSCSAG00000011281
Gene type
protein coding
RefSeq status
MODEL
Organism
Chlorocebus sabaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
49
Annotation release Status Assembly Chr Location
102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666041.1 (20983463..21108351)
100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 15 NC_023656.1 (48048785..48173120)

NW_023666041.1Genomic Context describing neighboring genes Neighboring gene U7 small nuclear RNA Neighboring gene transient receptor potential cation channel subfamily C member 1 Neighboring gene plastin 1 Neighboring gene eukaryotic translation initiation factor 2-alpha kinase 1-like Neighboring gene U1 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene 5'-3' exoribonuclease 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in telomere maintenance IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase ATR

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Vero_WHO_p1.0

Genomic

  1. NW_023666041.1 Reference Vero_WHO_p1.0

    Range
    20983463..21108351
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008008852.2 → XP_008007043.2  serine/threonine-protein kinase ATR isoform X1

    UniProtKB/TrEMBL
    A0A0D9RFU3
    Conserved Domains (4) summary
    smart00802
    Location:1119 → 1224
    UME; Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
    COG5032
    Location:2133 → 2644
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    cd00892
    Location:2293 → 2567
    PIKKc_ATR; Catalytic domain of Ataxia telangiectasia and Rad3-related proteins
    pfam02259
    Location:1771 → 2092
    FAT; FAT domain

  2. XM_008008853.2 → XP_008007044.2  serine/threonine-protein kinase ATR isoform X2

    UniProtKB/TrEMBL
    A0A0D9RFU3
    Conserved Domains (4) summary
    smart00802
    Location:1103 → 1208
    UME; Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
    COG5032
    Location:2117 → 2628
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    cd00892
    Location:2277 → 2551
    PIKKc_ATR; Catalytic domain of Ataxia telangiectasia and Rad3-related proteins
    pfam02259
    Location:1755 → 2076
    FAT; FAT domain

  3. XM_008008854.2 → XP_008007045.2  serine/threonine-protein kinase ATR isoform X3

    UniProtKB/TrEMBL
    A0A0D9RFU3
    Conserved Domains (4) summary
    smart00802
    Location:740 → 845
    UME; Domain in UVSB PI-3 kinase, MEI-41 and ESR-1
    COG5032
    Location:1754 → 2265
    TEL1; Phosphatidylinositol kinase or protein kinase, PI-3 family [Signal transduction mechanisms]
    cd00892
    Location:1914 → 2188
    PIKKc_ATR; Catalytic domain of Ataxia telangiectasia and Rad3-related proteins
    pfam02259
    Location:1392 → 1713
    FAT; FAT domain
Nucleotide Protein
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