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DLC1 DLC1 Rho GTPase activating protein [ Chlorocebus sabaeus (green monkey) ]

Gene ID: 103215714, updated on 11-Mar-2024

Summary

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Gene symbol
DLC1
Gene description
DLC1 Rho GTPase activating protein
Gene type
protein coding
RefSeq status
MODEL
Organism
Chlorocebus sabaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
22
Annotation release Status Assembly Chr Location
102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666052.1 (30700864..31128407)
100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 8 NC_023649.1 (11211230..11632278, complement)

NW_023666052.1Genomic Context describing neighboring genes Neighboring gene zinc finger protein 654-like Neighboring gene chromosome unknown C8orf48 homolog Neighboring gene SH3 domain and tetratricopeptide repeat-containing protein 1-like Neighboring gene tRNA methyltransferase 9B (putative)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables lipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane raft IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Vero_WHO_p1.0

Genomic

  1. NW_023666052.1 Reference Vero_WHO_p1.0

    Range
    30700864..31128407
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037983780.1 → XP_037839708.1  rho GTPase-activating protein 7 isoform X1

    Conserved Domains (3) summary
    cd08908
    Location:1315 → 1518
    START_STARD12-like; C-terminal lipid-binding START domain of mammalian STARD12 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
    cd09591
    Location:454 → 513
    SAM_DLC1; SAM domain of DLC1 subfamily
    cd04375
    Location:1072 → 1290
    RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

  2. XM_037983785.1 → XP_037839713.1  rho GTPase-activating protein 7 isoform X4

    UniProtKB/TrEMBL
    A0A0D9S0L9
    Conserved Domains (2) summary
    cd08908
    Location:804 → 1007
    START_STARD12-like; C-terminal lipid-binding START domain of mammalian STARD12 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
    cd04375
    Location:561 → 779
    RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

  3. XM_037983783.1 → XP_037839711.1  rho GTPase-activating protein 7 isoform X4

    UniProtKB/TrEMBL
    A0A0D9S0L9
    Conserved Domains (2) summary
    cd08908
    Location:804 → 1007
    START_STARD12-like; C-terminal lipid-binding START domain of mammalian STARD12 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
    cd04375
    Location:561 → 779
    RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

  4. XM_037983781.1 → XP_037839709.1  rho GTPase-activating protein 7 isoform X2

    Conserved Domains (3) summary
    cd08908
    Location:912 → 1115
    START_STARD12-like; C-terminal lipid-binding START domain of mammalian STARD12 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
    cd09591
    Location:51 → 110
    SAM_DLC1; SAM domain of DLC1 subfamily
    cd04375
    Location:669 → 887
    RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

  5. XM_037983782.1 → XP_037839710.1  rho GTPase-activating protein 7 isoform X3

    Conserved Domains (3) summary
    cd08908
    Location:878 → 1081
    START_STARD12-like; C-terminal lipid-binding START domain of mammalian STARD12 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
    cd09591
    Location:17 → 76
    SAM_DLC1; SAM domain of DLC1 subfamily
    cd04375
    Location:635 → 853
    RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

  6. XM_037983784.1 → XP_037839712.1  rho GTPase-activating protein 7 isoform X4

    UniProtKB/TrEMBL
    A0A0D9S0L9
    Conserved Domains (2) summary
    cd08908
    Location:804 → 1007
    START_STARD12-like; C-terminal lipid-binding START domain of mammalian STARD12 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
    cd04375
    Location:561 → 779
    RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

  7. XM_037983786.1 → XP_037839714.1  rho GTPase-activating protein 7 isoform X4

    UniProtKB/TrEMBL
    A0A0D9S0L9
    Conserved Domains (2) summary
    cd08908
    Location:804 → 1007
    START_STARD12-like; C-terminal lipid-binding START domain of mammalian STARD12 and related proteins, which also have an N-terminal Rho GTPase-activating protein (RhoGAP) domain
    cd04375
    Location:561 → 779
    RhoGAP_DLC1; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of DLC1-like proteins. DLC1 shows in vitro GAP activity towards RhoA and CDC42. Beside its C-terminal GAP domain, DLC1 also contains a SAM (sterile alpha motif) and a START ...

RNA

  1. XR_005235269.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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