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si:dkey-91m11.5 BCR activator of RhoGEF and GTPase [ Callorhinchus milii (elephant shark) ]

Gene ID: 103183970, updated on 11-Mar-2024

Summary

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Gene symbol
si:dkey-91m11.5
Gene description
BCR activator of RhoGEF and GTPase
See related
Ensembl:ENSCMIG00000012521
Gene type
protein coding
RefSeq status
MODEL
Organism
Callorhinchus milii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus
Also known as
bcr
Orthologs
zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
101 current IMCB_Cmil_1.0 (GCF_018977255.1) Unplaced Scaffold NW_024704749.1 (12950009..13013167, complement)
100 previous assembly Callorhinchus_milii-6.1.3 (GCF_000165045.1) Unplaced Scaffold NW_006890144.1 (41553..104683)

NW_024704749.1Genomic Context describing neighboring genes Neighboring gene transfer RNA arginine (anticodon CCU) Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1-like a Neighboring gene iron-sulfur cluster assembly enzyme a Neighboring gene spliceosome associated factor 3, U4/U6 recycling protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein
Names
BCR, RhoGEF and GTPase activating protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Callorhinchus milii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference IMCB_Cmil_1.0 Primary Assembly

Genomic

  1. NW_024704749.1 Reference IMCB_Cmil_1.0 Primary Assembly

    Range
    12950009..13013167 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007901742.2 → XP_007899933.1  PH_BCR_vertebrate and RhoGAP_Bcr domain-containing protein

    UniProtKB/TrEMBL
    A0A4W3ITC1, A0A4W3JB40
    Related
    ENSCMIP00000029558.1
    Conserved Domains (5) summary
    cd08686
    Location:958 → 1078
    C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
    cd04387
    Location:1097 → 1297
    RhoGAP_Bcr; RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, ...
    pfam00621
    Location:547 → 735
    RhoGEF; RhoGEF domain
    pfam09036
    Location:3 → 75
    Bcr-Abl_Oligo; Bcr-Abl oncoprotein oligomerization domain
    cl17171
    Location:729 → 922
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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