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RASAL2 RAS protein activator like 2 [ Erinaceus europaeus (western European hedgehog) ]

Gene ID: 103124989, updated on 11-Mar-2024

Summary

Gene symbol
RASAL2
Gene description
RAS protein activator like 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Erinaceus europaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae; Erinaceus
Orthologs
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Genomic context

Location:
chromosome: 9
Exon count:
18
Annotation release Status Assembly Chr Location
RS_2023_10 current mEriEur2.1 (GCF_950295315.1) 9 NC_080170.1 (42120856..42420537)
101 previous assembly EriEur2.0 (GCF_000296755.1) Unplaced Scaffold NW_006804770.1 (96463..401052, complement)

Chromosome 9 - NC_080170.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA70 Neighboring gene SEC16 homolog B, endoplasmic reticulum export factor Neighboring gene quinone oxidoreductase-like protein 2 Neighboring gene C-type lectin domain containing 20A Neighboring gene testis expressed 35

Genomic regions, transcripts, and products

General protein information

Preferred Names
ras GTPase-activating protein nGAP

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_950295315.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mEriEur2.1

Genomic

  1. NC_080170.1 Reference mEriEur2.1

    Range
    42120856..42420537
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007535754.3XP_007535816.1  ras GTPase-activating protein nGAP isoform X1

    UniProtKB/TrEMBL
    A0A1S3AIR9, A0A1S3WSR7
    Conserved Domains (6) summary
    cd04013
    Location:305444
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:435765
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    smart00323
    Location:428766
    RasGAP; GTPase-activator protein for Ras-like GTPases
    pfam12004
    Location:7551242
    DUF3498; Domain of unknown function (DUF3498)
    cl02488
    Location:11041252
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17171
    Location:180363
    PH-like; Pleckstrin homology-like domain
  2. XM_007535755.3XP_007535817.1  ras GTPase-activating protein nGAP isoform X2

    UniProtKB/TrEMBL
    A0A1S3AJ08, A0A1S3WSR7
    Conserved Domains (6) summary
    cd04013
    Location:305444
    C2_SynGAP_like; C2 domain present in Ras GTPase activating protein (GAP) family
    cd05136
    Location:435758
    RasGAP_DAB2IP; Ras-GTPase Activating Domain of DAB2IP and similar proteins
    smart00323
    Location:428759
    RasGAP; GTPase-activator protein for Ras-like GTPases
    pfam12004
    Location:7481235
    DUF3498; Domain of unknown function (DUF3498)
    cl02488
    Location:10971245
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cl17171
    Location:180363
    PH-like; Pleckstrin homology-like domain