U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

FARP1 FERM, ARH/RhoGEF and pleckstrin domain protein 1 [ Python bivittatus (Burmese python) ]

Gene ID: 103061789, updated on 11-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
FARP1
Gene description
FERM, ARH/RhoGEF and pleckstrin domain protein 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Python bivittatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Henophidia; Pythonidae; Python
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
26
Annotation release Status Assembly Chr Location
102 current Python_molurus_bivittatus-5.0.2 (GCF_000186305.1) Unplaced Scaffold NW_006532099.1 (281210..422111)

NW_006532099.1Genomic Context describing neighboring genes Neighboring gene ERCC excision repair 5, endonuclease Neighboring gene importin 5 Neighboring gene serine/threonine kinase 24 Neighboring gene uncharacterized LOC112541468 Neighboring gene solute carrier family 15 member 1

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_006532099 Unplaced Scaffold Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytoskeletal protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
FERM, ARHGEF and pleckstrin domain-containing protein 1
Names
FERM, RhoGEF (ARHGEF) and pleckstrin domain protein 1 (chondrocyte-derived)

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Python bivittatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Genomic

  1. NW_006532099.1 Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

    Range
    281210..422111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025170973.1 → XP_025026741.1  FERM, ARHGEF and pleckstrin domain-containing protein 1 isoform X1

    UniProtKB/TrEMBL
    A0A9F5IZU1
    Conserved Domains (6) summary
    smart00295
    Location:42 → 232
    B41; Band 4.1 homologues
    cd00160
    Location:542 → 729
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01220
    Location:754 → 861
    PH1_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 1
    cd13193
    Location:219 → 339
    FERM_C_FARP1-like; FERM domain C-lobe of FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins
    cd13235
    Location:931 → 1028
    PH2_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 2
    pfam08736
    Location:331 → 372
    FA; FERM adjacent (FA)

  2. XM_025170975.1 → XP_025026743.1  FERM, ARHGEF and pleckstrin domain-containing protein 1 isoform X2

    UniProtKB/TrEMBL
    A0A9F5IZQ7
    Conserved Domains (6) summary
    smart00295
    Location:42 → 232
    B41; Band 4.1 homologues
    cd00160
    Location:541 → 728
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01220
    Location:753 → 860
    PH1_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 1
    cd13193
    Location:219 → 339
    FERM_C_FARP1-like; FERM domain C-lobe of FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins
    cd13235
    Location:930 → 1027
    PH2_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 2
    pfam08736
    Location:331 → 372
    FA; FERM adjacent (FA)

  3. XM_025170986.1 → XP_025026754.1  FERM, ARHGEF and pleckstrin domain-containing protein 1 isoform X5

    UniProtKB/TrEMBL
    A0A9F5IKZ9
    Conserved Domains (6) summary
    smart00295
    Location:42 → 232
    B41; Band 4.1 homologues
    cd00160
    Location:538 → 725
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01220
    Location:750 → 857
    PH1_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 1
    cd13193
    Location:219 → 339
    FERM_C_FARP1-like; FERM domain C-lobe of FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins
    cd13235
    Location:927 → 1024
    PH2_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 2
    pfam08736
    Location:331 → 372
    FA; FERM adjacent (FA)

  4. XM_015889177.2 → XP_015744663.1  FERM, ARHGEF and pleckstrin domain-containing protein 1 isoform X3

    UniProtKB/TrEMBL
    A0A9F3W0F8
    Conserved Domains (9) summary
    smart00295
    Location:42 → 230
    B41; Band 4.1 homologues
    cd00160
    Location:540 → 727
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01220
    Location:752 → 859
    PH1_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 1
    cd13193
    Location:217 → 337
    FERM_C_FARP1-like; FERM domain C-lobe of FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins
    cd13235
    Location:929 → 1026
    PH2_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 2
    pfam00169
    Location:934 → 1025
    PH; PH domain
    pfam00373
    Location:127 → 230
    FERM_M; FERM central domain
    pfam08736
    Location:329 → 370
    FA; FERM adjacent (FA)
    pfam09379
    Location:44 → 107
    FERM_N; FERM N-terminal domain

  5. XM_007421300.3 → XP_007421362.1  FERM, ARHGEF and pleckstrin domain-containing protein 1 isoform X4

    UniProtKB/TrEMBL
    A0A9F2N5N0
    Conserved Domains (9) summary
    smart00295
    Location:42 → 230
    B41; Band 4.1 homologues
    cd00160
    Location:539 → 726
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd01220
    Location:751 → 858
    PH1_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 1
    cd13193
    Location:217 → 337
    FERM_C_FARP1-like; FERM domain C-lobe of FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins
    cd13235
    Location:928 → 1025
    PH2_FARP1-like; FERM, RhoGEF and pleckstrin domain-containing protein 1 and related proteins Pleckstrin Homology (PH) domain, repeat 2
    pfam00169
    Location:933 → 1024
    PH; PH domain
    pfam00373
    Location:127 → 230
    FERM_M; FERM central domain
    pfam08736
    Location:329 → 370
    FA; FERM adjacent (FA)
    pfam09379
    Location:44 → 107
    FERM_N; FERM N-terminal domain

RNA

  1. XR_003085445.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.