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ITM2A integral membrane protein 2A [ Physeter catodon (sperm whale) ]

Gene ID: 102993430, updated on 10-Mar-2024

Summary

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Gene symbol
ITM2A
Gene description
integral membrane protein 2A
See related
Ensembl:ENSPCTG00005016548
Gene type
protein coding
RefSeq status
MODEL
Organism
Physeter catodon
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Physeteridae; Physeter
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 21
Exon count:
6
Annotation release Status Assembly Chr Location
RS_2023_04 current ASM283717v5 (GCF_002837175.3) 21 NC_041234.1 (54883827..54889825, complement)
102 previous assembly ASM283717v2 (GCF_002837175.2) 21 NC_041234.1 (54883827..54889825, complement)

Chromosome 21 - NC_041234.1Genomic Context describing neighboring genes Neighboring gene putative P2Y purinoceptor 10 Neighboring gene G protein-coupled receptor 174 Neighboring gene U6 spliceosomal RNA Neighboring gene T-box transcription factor 22

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in negative regulation of amyloid precursor protein biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in Golgi apparatus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular exosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
integral membrane protein 2A

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002837175.3-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM283717v5 Primary Assembly

Genomic

  1. NC_041234.1 Reference ASM283717v5 Primary Assembly

    Range
    54883827..54889825 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007115018.2 → XP_007115080.1  integral membrane protein 2A isoform X1

    UniProtKB/TrEMBL
    A0A2Y9F4K1
    Related
    ENSPCTP00005023214.1, ENSPCTT00005025566.1
    Conserved Domains (1) summary
    smart01039
    Location:133 → 225
    BRICHOS; The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer

  2. XM_007115020.3 → XP_007115082.1  integral membrane protein 2A isoform X2

    UniProtKB/TrEMBL
    A0A2Y9F4R3
    Related
    ENSPCTP00005023229.1, ENSPCTT00005025584.1
    Conserved Domains (1) summary
    smart01039
    Location:89 → 181
    BRICHOS; The BRICHOS domain is found in a variety of proteins implicated in dementia, respiratory distress and cancer
Nucleotide Protein
Heading Accession and Version

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