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ARHGEF40 Rho guanine nucleotide exchange factor 40 [ Physeter catodon (sperm whale) ]

Gene ID: 102987855, updated on 10-Mar-2024

Summary

Gene symbol
ARHGEF40
Gene description
Rho guanine nucleotide exchange factor 40
See related
Ensembl:ENSPCTG00005003451
Gene type
protein coding
RefSeq status
MODEL
Organism
Physeter catodon
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Physeteridae; Physeter
Orthologs
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Genomic context

Location:
chromosome: 11
Exon count:
24
Annotation release Status Assembly Chr Location
RS_2023_04 current ASM283717v5 (GCF_002837175.3) 11 NC_041224.1 (105964585..105987068)
102 previous assembly ASM283717v2 (GCF_002837175.2) 11 NC_041224.1 (105964582..105986634)

Chromosome 11 - NC_041224.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 39 member 2 Neighboring gene methyltransferase like 17 Neighboring gene zinc finger protein 219 Neighboring gene transmembrane protein 253

Genomic regions, transcripts, and products

General protein information

Preferred Names
rho guanine nucleotide exchange factor 40

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002837175.3-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM283717v5 Primary Assembly

Genomic

  1. NC_041224.1 Reference ASM283717v5 Primary Assembly

    Range
    105964585..105987068
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007104787.4XP_007104849.1  rho guanine nucleotide exchange factor 40 isoform X1

    See identical proteins and their annotated locations for XP_007104849.1

    UniProtKB/TrEMBL
    A0A2Y9ELH1
    Conserved Domains (4) summary
    cd00176
    Location:785971
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd13242
    Location:12451380
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    pfam00169
    Location:12701368
    PH; PH domain
    cl02571
    Location:10871179
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
  2. XM_007104788.4XP_007104850.1  rho guanine nucleotide exchange factor 40 isoform X1

    See identical proteins and their annotated locations for XP_007104850.1

    UniProtKB/TrEMBL
    A0A2Y9ELH1
    Conserved Domains (4) summary
    cd00176
    Location:785971
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd13242
    Location:12451380
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    pfam00169
    Location:12701368
    PH; PH domain
    cl02571
    Location:10871179
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
  3. XM_007104789.4XP_007104851.1  rho guanine nucleotide exchange factor 40 isoform X2

    UniProtKB/TrEMBL
    A0A2Y9EM31
    Related
    ENSPCTP00005005188.1, ENSPCTT00005005708.1
    Conserved Domains (4) summary
    cd00176
    Location:785971
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd13242
    Location:12451380
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    pfam00169
    Location:12701368
    PH; PH domain
    cl02571
    Location:10871179
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
  4. XM_007104790.4XP_007104852.1  rho guanine nucleotide exchange factor 40 isoform X3

    UniProtKB/TrEMBL
    A0A2Y9EN32
    Conserved Domains (4) summary
    cd00176
    Location:785971
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd13242
    Location:12451380
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    pfam00169
    Location:12701368
    PH; PH domain
    cl02571
    Location:10871179
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
  5. XM_007104791.4XP_007104853.1  rho guanine nucleotide exchange factor 40 isoform X4

    UniProtKB/TrEMBL
    A0A2Y9ELI2
    Conserved Domains (4) summary
    cd00176
    Location:785971
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd13242
    Location:12451380
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    pfam00169
    Location:12701368
    PH; PH domain
    cl02571
    Location:10871179
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
  6. XM_028495593.2XP_028351394.1  rho guanine nucleotide exchange factor 40 isoform X5

    UniProtKB/TrEMBL
    A0A455BR04
    Conserved Domains (3) summary
    cd00176
    Location:593779
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd13242
    Location:10531188
    PH_puratrophin-1; Puratrophin-1 pleckstrin homology (PH) domain
    cl02571
    Location:895987
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.