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SEMA7A semaphorin 7A (JohnMiltonHagen blood group) [ Physeter catodon (sperm whale) ]

Gene ID: 102978688, updated on 10-Mar-2024

Summary

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Gene symbol
SEMA7A
Gene description
semaphorin 7A (JohnMiltonHagen blood group)
See related
Ensembl:ENSPCTG00005015468
Gene type
protein coding
RefSeq status
MODEL
Organism
Physeter catodon
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Physeteridae; Physeter
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 11
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_04 current ASM283717v5 (GCF_002837175.3) 11 NC_041224.1 (65894292..65916971, complement)
102 previous assembly ASM283717v2 (GCF_002837175.2) 11 NC_041224.1 (65894298..65916971, complement)

Chromosome 11 - NC_041224.1Genomic Context describing neighboring genes Neighboring gene signaling receptor and transporter of retinol STRA6 Neighboring gene cholesterol side-chain cleavage enzyme, mitochondrial Neighboring gene ubiquitin-like protein 7 Neighboring gene ubiquitin like 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chemorepellent activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables semaphorin receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative chemotaxis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of axon extension involved in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neural crest cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ERK1 and ERK2 cascade IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of axon extension IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macrophage cytokine production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in semaphorin-plexin signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
semaphorin-7A
Names
semaphorin 7A (John Milton Hagen blood group)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002837175.3-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM283717v5 Primary Assembly

Genomic

  1. NC_041224.1 Reference ASM283717v5 Primary Assembly

    Range
    65894292..65916971 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_055088115.1 → XP_054944090.1  semaphorin-7A isoform X3

    UniProtKB/TrEMBL
    A0A9W2WY83

  2. XM_024128863.3 → XP_023984631.1  semaphorin-7A isoform X1

    UniProtKB/TrEMBL
    A0A2Y9T141
    Related
    ENSPCTP00005021705.1, ENSPCTT00005023908.1
    Conserved Domains (3) summary
    cd11243
    Location:70 → 488
    Sema_7A; The Sema domain, a protein interacting module, of semaphorin 7A (Sema7A, also called CD108)
    pfam01437
    Location:490 → 539
    PSI; Plexin repeat
    pfam13927
    Location:542 → 612
    Ig_3; Immunoglobulin domain

  3. XM_055088114.1 → XP_054944089.1  semaphorin-7A isoform X2

    UniProtKB/TrEMBL
    A0A9W2WY73

  4. XM_055088116.1 → XP_054944091.1  semaphorin-7A isoform X4

    UniProtKB/TrEMBL
    A0A9W2WXY9
Nucleotide Protein
Heading Accession and Version

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