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ISL1 ISL LIM homeobox 1 [ Panthera tigris (tiger) ]

Gene ID: 102956435, updated on 10-Mar-2024

Summary

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Gene symbol
ISL1
Gene description
ISL LIM homeobox 1
See related
Ensembl:ENSPTIG00000019996
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: A1
Exon count:
7
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) A1 NC_056660.1 (200343030..200373391, complement)

Chromosome A1 - NC_056660.1Genomic Context describing neighboring genes Neighboring gene U2 spliceosomal RNA Neighboring gene peptidyl-prolyl cis-trans isomerase A-like Neighboring gene uncharacterized LOC122240992 Neighboring gene uncharacterized LOC122231797 Neighboring gene poly(ADP-ribose) polymerase family member 8

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056660.1 Chromosome A1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axonogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in neuron fate specification IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
insulin gene enhancer protein ISL-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056660.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    200343030..200373391 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042960285.1 → XP_042816219.1  insulin gene enhancer protein ISL-1 isoform X3

    Conserved Domains (3) summary
    cd09366
    Location:17 → 71
    LIM1_Isl; The first LIM domain of Isl, a member of LHX protein family
    cd09374
    Location:79 → 133
    LIM2_Isl; The second LIM domain of Isl, a member of LHX protein family
    smart00389
    Location:181 → 237
    HOX; Homeodomain

  2. XM_042960280.1 → XP_042816214.1  insulin gene enhancer protein ISL-1 isoform X2

    Conserved Domains (4) summary
    cd09366
    Location:17 → 71
    LIM1_Isl; The first LIM domain of Isl, a member of LHX protein family
    cd09374
    Location:79 → 133
    LIM2_Isl; The second LIM domain of Isl, a member of LHX protein family
    smart00389
    Location:181 → 237
    HOX; Homeodomain
    COG5576
    Location:145 → 268
    COG5576; Homeodomain-containing transcription factor [Transcription]

  3. XM_007076651.3 → XP_007076713.1  insulin gene enhancer protein ISL-1 isoform X1

    See identical proteins and their annotated locations for XP_007076713.1

    UniProtKB/TrEMBL
    A0A8C9KL19
    Related
    ENSPTIP00000023596.1
    Conserved Domains (3) summary
    cd09366
    Location:17 → 71
    LIM1_Isl; The first LIM domain of Isl, a member of LHX protein family
    cd09374
    Location:79 → 133
    LIM2_Isl; The second LIM domain of Isl, a member of LHX protein family
    smart00389
    Location:181 → 237
    HOX; Homeodomain
Nucleotide Protein
Heading Accession and Version

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