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FAN1 FANCD2 and FANCI associated nuclease 1 [ Panthera tigris (tiger) ]

Gene ID: 102948793, updated on 10-Mar-2024

Summary

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Gene symbol
FAN1
Gene description
FANCD2 and FANCI associated nuclease 1
See related
Ensembl:ENSPTIG00000017410
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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See FAN1 in Genome Data Viewer
Location:
chromosome: B3
Exon count:
20
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) B3 NC_056665.1 (21325062..21359874)

Chromosome B3 - NC_056665.1Genomic Context describing neighboring genes Neighboring gene M-phase phosphoprotein 10 Neighboring gene 40S ribosomal protein S29-like Neighboring gene myotubularin related protein 10 Neighboring gene uncharacterized LOC122239408 Neighboring gene transient receptor potential cation channel subfamily M member 1 Neighboring gene U2 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056665.1 Chromosome B3 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 5'-3' exonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 5'-flap endonuclease activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables flap-structured DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in interstrand cross-link repair IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fanconi-associated nuclease 1
Names
FANCD2/FANCI-associated nuclease 1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056665.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    21325062..21359874
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042988253.1 → XP_042844187.1  fanconi-associated nuclease 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C9KBJ1
    Conserved Domains (2) summary
    smart00990
    Location:924 → 1053
    VRR_NUC; This model contains proteins with the VRR-NUC domain
    cl02765
    Location:41 → 62
    zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain

  2. XM_042988252.1 → XP_042844186.1  fanconi-associated nuclease 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C9KBJ1
    Conserved Domains (2) summary
    smart00990
    Location:924 → 1053
    VRR_NUC; This model contains proteins with the VRR-NUC domain
    cl02765
    Location:41 → 62
    zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain

  3. XM_007095871.2 → XP_007095933.1  fanconi-associated nuclease 1 isoform X3

    See identical proteins and their annotated locations for XP_007095933.1

    UniProtKB/TrEMBL
    A0A8C9KBJ1, A0A8C9KC16
    Related
    ENSPTIP00000019695.1
    Conserved Domains (3) summary
    pfam09528
    Location:96 → 486
    Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
    smart00734
    Location:41 → 62
    ZnF_Rad18; Rad18-like CCHC zinc finger
    pfam08774
    Location:921 → 1018
    VRR_NUC; VRR-NUC domain

  4. XM_042988257.1 → XP_042844191.1  fanconi-associated nuclease 1 isoform X4

    UniProtKB/TrEMBL
    A0A8C9KBJ1
    Conserved Domains (2) summary
    smart00990
    Location:880 → 1009
    VRR_NUC; This model contains proteins with the VRR-NUC domain
    cl02765
    Location:41 → 62
    zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain

  5. XM_042988256.1 → XP_042844190.1  fanconi-associated nuclease 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C9KBJ1
    Conserved Domains (2) summary
    smart00990
    Location:924 → 982
    VRR_NUC; This model contains proteins with the VRR-NUC domain
    cl02765
    Location:41 → 62
    zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain

  6. XM_042988255.1 → XP_042844189.1  fanconi-associated nuclease 1 isoform X2

    UniProtKB/TrEMBL
    A0A8C9KBJ1
    Conserved Domains (2) summary
    smart00990
    Location:924 → 982
    VRR_NUC; This model contains proteins with the VRR-NUC domain
    cl02765
    Location:41 → 62
    zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain

  7. XM_042988258.1 → XP_042844192.1  fanconi-associated nuclease 1 isoform X5

    UniProtKB/TrEMBL
    A0A8C9KBJ1
    Conserved Domains (1) summary
    smart00734
    Location:41 → 62
    ZnF_Rad18; Rad18-like CCHC zinc finger

  8. XM_042988259.1 → XP_042844193.1  fanconi-associated nuclease 1 isoform X6

    UniProtKB/TrEMBL
    A0A8C9KBJ1
    Conserved Domains (1) summary
    smart00734
    Location:41 → 62
    ZnF_Rad18; Rad18-like CCHC zinc finger

  9. XM_042988261.1 → XP_042844195.1  fanconi-associated nuclease 1 isoform X8

    Conserved Domains (1) summary
    smart00734
    Location:41 → 62
    ZnF_Rad18; Rad18-like CCHC zinc finger

  10. XM_042988260.1 → XP_042844194.1  fanconi-associated nuclease 1 isoform X7

    Conserved Domains (1) summary
    smart00734
    Location:41 → 62
    ZnF_Rad18; Rad18-like CCHC zinc finger

  11. XM_042988254.1 → XP_042844188.1  fanconi-associated nuclease 1 isoform X1

    UniProtKB/TrEMBL
    A0A8C9KBJ1
    Conserved Domains (2) summary
    smart00990
    Location:924 → 1053
    VRR_NUC; This model contains proteins with the VRR-NUC domain
    cl02765
    Location:41 → 62
    zf-WRNIP1_ubi; Werner helicase-interacting protein 1 ubiquitin-binding domain
Nucleotide Protein
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